A Handbook for DNA-Encoded Chemistry
Theory and Applications for Exploring Chemical Space and Drug Discovery
Nonfiction, Science & Nature, Science, Chemistry, Technical & Industrial, Organic, Biological Sciences, Biochemistry
| Author: | Robert A. Goodnow Jr. | ISBN: | 9781118832677 |
| Publisher: | Wiley | Publication: | April 10, 2014 |
| Imprint: | Wiley | Language: | English |
| Author: | Robert A. Goodnow Jr. |
| ISBN: | 9781118832677 |
| Publisher: | Wiley |
| Publication: | April 10, 2014 |
| Imprint: | Wiley |
| Language: | English |
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book:
- Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry
- Helps chemists generate and screen novel chemical libraries of large size and quality
- Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry
- Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery
- Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book:
- Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry
- Helps chemists generate and screen novel chemical libraries of large size and quality
- Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry
- Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery
- Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
