A Handbook of Transcription Factors

Nonfiction, Science & Nature, Science, Other Sciences, Molecular Biology, Biological Sciences, Biochemistry, Health & Well Being, Medical
Cover of the book A Handbook of Transcription Factors by , Springer Netherlands
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Author: ISBN: 9789048190690
Publisher: Springer Netherlands Publication: May 10, 2011
Imprint: Springer Language: English
Author:
ISBN: 9789048190690
Publisher: Springer Netherlands
Publication: May 10, 2011
Imprint: Springer
Language: English

Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes.  In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. 

This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.

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Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes.  In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. 

This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.

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