ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins

Applications in Drug Discovery and Development

Nonfiction, Health & Well Being, Medical, Medical Science, Biotechnology, Science & Nature, Science, Biological Sciences, Biochemistry, Pharmacology
Cover of the book ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins by Honghui Zhou, Frank-Peter Theil, Wiley
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Honghui Zhou, Frank-Peter Theil ISBN: 9781118898741
Publisher: Wiley Publication: October 26, 2015
Imprint: Wiley Language: English
Author: Honghui Zhou, Frank-Peter Theil
ISBN: 9781118898741
Publisher: Wiley
Publication: October 26, 2015
Imprint: Wiley
Language: English

With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs.

• Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs
• Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective
• Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines
• Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan
• Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs.

• Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs
• Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective
• Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines
• Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan
• Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain

More books from Wiley

Cover of the book Teach Yourself VISUALLY Salesforce.com by Honghui Zhou, Frank-Peter Theil
Cover of the book Improving Healthcare Through Advocacy by Honghui Zhou, Frank-Peter Theil
Cover of the book Functionalization of Semiconductor Surfaces by Honghui Zhou, Frank-Peter Theil
Cover of the book Bike Repair and Maintenance For Dummies by Honghui Zhou, Frank-Peter Theil
Cover of the book Linux Command Line and Shell Scripting Bible by Honghui Zhou, Frank-Peter Theil
Cover of the book Future War by Honghui Zhou, Frank-Peter Theil
Cover of the book Global Asian City by Honghui Zhou, Frank-Peter Theil
Cover of the book Basics of Analytical Chemistry and Chemical Equilibria by Honghui Zhou, Frank-Peter Theil
Cover of the book Renewable Energy by Honghui Zhou, Frank-Peter Theil
Cover of the book Genetic and Evolutionary Computation by Honghui Zhou, Frank-Peter Theil
Cover of the book Symptoms in the Pharmacy by Honghui Zhou, Frank-Peter Theil
Cover of the book The Traits of Today's CFO by Honghui Zhou, Frank-Peter Theil
Cover of the book Sequencing Apple's DNA by Honghui Zhou, Frank-Peter Theil
Cover of the book iOS Hacker's Handbook by Honghui Zhou, Frank-Peter Theil
Cover of the book The Cult of the Leader by Honghui Zhou, Frank-Peter Theil
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy