ADMET for Medicinal Chemists

A Practical Guide

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology
Cover of the book ADMET for Medicinal Chemists by , Wiley
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Author: ISBN: 9780470922811
Publisher: Wiley Publication: February 15, 2011
Imprint: Wiley Language: English
Author:
ISBN: 9780470922811
Publisher: Wiley
Publication: February 15, 2011
Imprint: Wiley
Language: English

This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists. In addition, the scientific principles and the tools utilized by ADME scientists in a discovery setting, as applied to medicinal chemistry and structure modification to improve drug-like properties of drug candidates, are examined.

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This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists. In addition, the scientific principles and the tools utilized by ADME scientists in a discovery setting, as applied to medicinal chemistry and structure modification to improve drug-like properties of drug candidates, are examined.

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