Anxiolytic β-Carbolines

From Molecular Biology to the Clinic

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology, Specialties, Psychiatry
Cover of the book Anxiolytic β-Carbolines by , Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783642784514
Publisher: Springer Berlin Heidelberg Publication: March 7, 2013
Imprint: Springer Language: English
Author:
ISBN: 9783642784514
Publisher: Springer Berlin Heidelberg
Publication: March 7, 2013
Imprint: Springer
Language: English

Since the discovery some 15 years ago of benzodiazepine modulatory sites associated with GABA A receptors, great effort has gone into understanding their molecular pharmacology and into developing new anxiolytic drugs that interact selectively with them. Prominent in this research has beenthe discovery that ~-carbolines, a different chemical class from benzodiazepines, also act at these receptors but that their effects are sometimes quite different from those of the benzodiazepines.This book documents the latest discoveries in the molecular biology of the GABA A receptor and reveals how an integration of the results of research inmolecular biology, synthetic chemistry, biochemical and behavioral pharmacology, and clinical pharmacology has paved the way forthe development of ~-carbolines from substances inducing anxiety and convulsions to a novel therapy for anxiety states, achieving a behavioral selectivity through selective actions at subtypes of receptors.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Since the discovery some 15 years ago of benzodiazepine modulatory sites associated with GABA A receptors, great effort has gone into understanding their molecular pharmacology and into developing new anxiolytic drugs that interact selectively with them. Prominent in this research has beenthe discovery that ~-carbolines, a different chemical class from benzodiazepines, also act at these receptors but that their effects are sometimes quite different from those of the benzodiazepines.This book documents the latest discoveries in the molecular biology of the GABA A receptor and reveals how an integration of the results of research inmolecular biology, synthetic chemistry, biochemical and behavioral pharmacology, and clinical pharmacology has paved the way forthe development of ~-carbolines from substances inducing anxiety and convulsions to a novel therapy for anxiety states, achieving a behavioral selectivity through selective actions at subtypes of receptors.

More books from Springer Berlin Heidelberg

Cover of the book Practice of Intramedullary Locked Nails by
Cover of the book Spielregeln für Beruf und Karriere by
Cover of the book Resonant X-Ray Scattering in Correlated Systems by
Cover of the book Chinese Lawmaking: From Non-communicative to Communicative by
Cover of the book Veterinäronkologie kompakt by
Cover of the book Anwendungstechnologie Aluminium by
Cover of the book Aplastic Anemia by
Cover of the book Keratoprostheses and Artificial Corneas by
Cover of the book Clinical Atlas of Skin Tumors by
Cover of the book The Tropospheric Chemistry of Ozone in the Polar Regions by
Cover of the book Sport in the Modern World — Chances and Problems by
Cover of the book Erneuerbare Energien by
Cover of the book Autophagy in Infection and Immunity by
Cover of the book Cooperative Optical Non-Linearity in a Blockaded Rydberg Ensemble by
Cover of the book The Economics of Contemporary Art by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy