Autoimmune Liver Diseases

Perspectives from Japan

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Gastroenterology, General
Cover of the book Autoimmune Liver Diseases by , Springer Japan
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9784431547891
Publisher: Springer Japan Publication: August 21, 2014
Imprint: Springer Language: English
Author:
ISBN: 9784431547891
Publisher: Springer Japan
Publication: August 21, 2014
Imprint: Springer
Language: English

Autoimmune Liver Diseases summarizes the recent high-impact research and clinical findings obtained in Japan in the study and treatment of autoimmune liver diseases. Although these disorders are relatively rare, they are recognized as an important group of refractory liver diseases, the most common of which are autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). The book therefore comprises two major sections, one dealing with AIH, the other with PBC.

AIH in Japanese patients creates a unique disease population, as its clinical features are different from those of Western patients resulting from the different genetic background of the two patient populations. Also, mouse models of neonatal thymectomy-PD-1 knockout mice, clinical analyses of acute hepatitis-like manifestations, and research findings on IgG4-related autoimmune hepatitis have been reported in Japan and are included in this book. A disease-susceptibility gene specific to Japanese PBC patients has also recently been discovered. Because of the relatively homogeneous population of Japan, analyses conducted with Japanese PBC patients have yielded findings that are highly relevant to the pathogenesis of the disease.

Furthermore, new pathological staging criteria, anti-gp210 antibodies and the basis they provide for improved accuracy of prognosis, treatment with bezafibrate, and the outcomes of living-donor liver transplantation are also presented here. This volume therefore serves as a useful resource not only for hepatologists, but also for researchers, clinical residents, and medical students both in Japan and in other countries.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Autoimmune Liver Diseases summarizes the recent high-impact research and clinical findings obtained in Japan in the study and treatment of autoimmune liver diseases. Although these disorders are relatively rare, they are recognized as an important group of refractory liver diseases, the most common of which are autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). The book therefore comprises two major sections, one dealing with AIH, the other with PBC.

AIH in Japanese patients creates a unique disease population, as its clinical features are different from those of Western patients resulting from the different genetic background of the two patient populations. Also, mouse models of neonatal thymectomy-PD-1 knockout mice, clinical analyses of acute hepatitis-like manifestations, and research findings on IgG4-related autoimmune hepatitis have been reported in Japan and are included in this book. A disease-susceptibility gene specific to Japanese PBC patients has also recently been discovered. Because of the relatively homogeneous population of Japan, analyses conducted with Japanese PBC patients have yielded findings that are highly relevant to the pathogenesis of the disease.

Furthermore, new pathological staging criteria, anti-gp210 antibodies and the basis they provide for improved accuracy of prognosis, treatment with bezafibrate, and the outcomes of living-donor liver transplantation are also presented here. This volume therefore serves as a useful resource not only for hepatologists, but also for researchers, clinical residents, and medical students both in Japan and in other countries.

More books from Springer Japan

Cover of the book Governance of Urban Sustainability Transitions by
Cover of the book The Political Economy of Fiscal Consolidation in Japan by
Cover of the book Dementia with Lewy Bodies by
Cover of the book Liver Cirrhosis by
Cover of the book Ecological Impacts of Tsunamis on Coastal Ecosystems by
Cover of the book Hearing Impairment by
Cover of the book Applied Data-Centric Social Sciences by
Cover of the book Metallomics by
Cover of the book Retinal and Choroidal Vascular Changes and Systemic Diseases in Rats by
Cover of the book Supercritical-Pressure Light Water Cooled Reactors by
Cover of the book Protein Modifications in Pathogenic Dysregulation of Signaling by
Cover of the book Atlas of Exocrine Pancreatic Tumors by
Cover of the book Search for Charginos Nearly Mass-Degenerate with the Lightest Neutralino by
Cover of the book Computing and Monitoring in Anesthesia and Intensive Care by
Cover of the book Dendrites by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy