Autoimmunity and the Pathogenesis of Diabetes

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Specialties, Internal Medicine, Endocrinology & Metabolism
Cover of the book Autoimmunity and the Pathogenesis of Diabetes by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781461232186
Publisher: Springer New York Publication: December 6, 2012
Imprint: Springer Language: English
Author:
ISBN: 9781461232186
Publisher: Springer New York
Publication: December 6, 2012
Imprint: Springer
Language: English

It has been a challenge for us to edit this volume of Endocrinology and Metabo­ lism: Progress in Research and Clinical Practice. The topic of the pathogenesis of insulin-dependent, type I diabetes mellitus is particularly appropriate for this series, since advances in this area have been made, to a large extent, by applying state-of-the-art laboratory techniques to clinical samples. Over the last several years, a number of lines of evidence have been gathered, suggesting that classic type I diabetes mellitus results from the autoimmune des­ truction of pancreatic beta-cells in genetically susceptible individuals. This hypothesis is particularly appealing because it offers a rational approach to the prevention of diabetes by immunosuppression. We have tried to present a balanced, authoritative summary of the information currently available to support the autoimmune hypothesis for the pathogenesis of human type I diabetes, to place this information in historical perspective, to include relevant information from animal models of type I diabetes in which more invasive experimentation is ethical, and, finally, to update the reader on the current status of attempts to intervene in the progression of diabetes with immunosuppressive drugs. New York, New York Fredda Ginsberg-Fellner Robert C. McEvoy Contents Preface.. . . .. .. .. . . . . . . . . . . . . ... . . . . . . . . . . . .. . . . . . . .. . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Xl . . . . . . . . . . . . . 1. The Autoimmune Hypothesis of Insulin-Dependent Diabetes: 1965 to the Present . . . . . . . . . . . . ..................... . . . . . .

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

It has been a challenge for us to edit this volume of Endocrinology and Metabo­ lism: Progress in Research and Clinical Practice. The topic of the pathogenesis of insulin-dependent, type I diabetes mellitus is particularly appropriate for this series, since advances in this area have been made, to a large extent, by applying state-of-the-art laboratory techniques to clinical samples. Over the last several years, a number of lines of evidence have been gathered, suggesting that classic type I diabetes mellitus results from the autoimmune des­ truction of pancreatic beta-cells in genetically susceptible individuals. This hypothesis is particularly appealing because it offers a rational approach to the prevention of diabetes by immunosuppression. We have tried to present a balanced, authoritative summary of the information currently available to support the autoimmune hypothesis for the pathogenesis of human type I diabetes, to place this information in historical perspective, to include relevant information from animal models of type I diabetes in which more invasive experimentation is ethical, and, finally, to update the reader on the current status of attempts to intervene in the progression of diabetes with immunosuppressive drugs. New York, New York Fredda Ginsberg-Fellner Robert C. McEvoy Contents Preface.. . . .. .. .. . . . . . . . . . . . . ... . . . . . . . . . . . .. . . . . . . .. . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Xl . . . . . . . . . . . . . 1. The Autoimmune Hypothesis of Insulin-Dependent Diabetes: 1965 to the Present . . . . . . . . . . . . ..................... . . . . . .

More books from Springer New York

Cover of the book Qualitative Comparative Analysis with R by
Cover of the book Mucosal Immunology of Acute Bacterial Pneumonia by
Cover of the book Psychosocial Impact of Polygamy in the Middle East by
Cover of the book High Density Lipoproteins, Dyslipidemia, and Coronary Heart Disease by
Cover of the book Behavioral Approaches to Chronic Disease in Adolescence by
Cover of the book Reforming Juvenile Justice by
Cover of the book China’s Strategy in Space by
Cover of the book Tallgrass Prairie Restoration in the Midwestern and Eastern United States by
Cover of the book Advances in Communication Research to Reduce Childhood Obesity by
Cover of the book Statistical Modeling and Computation by
Cover of the book Educational Media and Technology Yearbook by
Cover of the book Contemporary Perspectives on Lesbian, Gay, and Bisexual Identities by
Cover of the book Pediatric Cardiology and Pulmonology by
Cover of the book Bergey's Manual of Systematic Bacteriology by
Cover of the book Suicide Among Child Sex Offenders by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy