Autophagy Networks in Inflammation

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Science & Nature, Science, Other Sciences, Molecular Biology
Cover of the book Autophagy Networks in Inflammation by , Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783319300795
Publisher: Springer International Publishing Publication: August 17, 2016
Imprint: Springer Language: English
Author:
ISBN: 9783319300795
Publisher: Springer International Publishing
Publication: August 17, 2016
Imprint: Springer
Language: English

Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direct interactions between autophagy proteins and immune signalling molecules have also been demonstrated. Defects in autophagy - similar to cancer, neurodegenerative diseases and aging - through autophagy gene mutation and/or microbial antagonism, may underlie the pathogenesis of many infectious diseases and inflammatory syndromes. In spite of the increasing awareness of the importance of autophagy in these pathophysiological conditions, this process remains underestimated and is often overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these diseases are still poorly understood. This book reviews the recent advances regarding the functions of the autophagy pathway and autophagy proteins in immunity and inflammation, focusing on their role in self-nonself distinction, their implications in innate and adaptive immune responses and their dysregulation in the pathology of certain inflammatory and autoimmune diseases.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direct interactions between autophagy proteins and immune signalling molecules have also been demonstrated. Defects in autophagy - similar to cancer, neurodegenerative diseases and aging - through autophagy gene mutation and/or microbial antagonism, may underlie the pathogenesis of many infectious diseases and inflammatory syndromes. In spite of the increasing awareness of the importance of autophagy in these pathophysiological conditions, this process remains underestimated and is often overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these diseases are still poorly understood. This book reviews the recent advances regarding the functions of the autophagy pathway and autophagy proteins in immunity and inflammation, focusing on their role in self-nonself distinction, their implications in innate and adaptive immune responses and their dysregulation in the pathology of certain inflammatory and autoimmune diseases.

More books from Springer International Publishing

Cover of the book Building the Impact Economy by
Cover of the book Big Data, Cloud Computing, and Data Science Engineering by
Cover of the book An Economic Inquiry into the Nonlinear Behaviors of Nations by
Cover of the book Information Technology for Management: Emerging Research and Applications by
Cover of the book Grate-Fired Energy Crop Conversion by
Cover of the book Advances in Research on Fertilization Management of Vegetable Crops by
Cover of the book Numerical Approximation of the Magnetoquasistatic Model with Uncertainties by
Cover of the book Staphylococcus aureus by
Cover of the book Comprehensive Cardiovascular Medicine in the Primary Care Setting by
Cover of the book Advances in Human Factors and Simulation by
Cover of the book Integrating Business Process Models and Rules by
Cover of the book Lucky Boy in the Lucky Country by
Cover of the book Privacy and Identity Management. Facing up to Next Steps by
Cover of the book Architecture of Computing Systems - ARCS 2017 by
Cover of the book Stress Fractures in Athletes by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy