by
Ying Yuan, Hoang Q. Nguyen, Peter F. Thall
Language: English
Release Date: December 19, 2017
Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine...