Clinical Application of Radiolabelled Platelets

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Hematology, Radiology & Nuclear Medicine
Cover of the book Clinical Application of Radiolabelled Platelets by , Springer Netherlands
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9789400905818
Publisher: Springer Netherlands Publication: December 6, 2012
Imprint: Springer Language: English
Author:
ISBN: 9789400905818
Publisher: Springer Netherlands
Publication: December 6, 2012
Imprint: Springer
Language: English

AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D.

More books from Springer Netherlands

Cover of the book Data-based Decision Making in Education by
Cover of the book Le monde social selon Husserl by
Cover of the book Visual Mathematics and Cyberlearning by
Cover of the book MACPF/CDC Proteins - Agents of Defence, Attack and Invasion by
Cover of the book Irregular Negatives, Implicatures, and Idioms by
Cover of the book Reason, Spirit and the Sacral in the New Enlightenment by
Cover of the book The Search for a Methodology of Social Science by
Cover of the book Photosynthesis in Bryophytes and Early Land Plants by
Cover of the book Environmental Deterioration and Human Health by
Cover of the book Mexican American and Immigrant Poverty in the United States by
Cover of the book Mercury — Cadmium — Lead Handbook for Sustainable Heavy Metals Policy and Regulation by
Cover of the book Pediatric Oncology 1 by
Cover of the book The Principle of Proportionality by
Cover of the book Clinical Use of Antibodies by
Cover of the book Reconstruction of Wave-Particle Duality and its Implications for General Chemistry Textbooks by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy