Clinical Aspects of Albumin

Nonfiction, Health & Well Being, Medical, Specialties, Critical Care, Internal Medicine, Gastroenterology
Cover of the book Clinical Aspects of Albumin by , Springer Netherlands
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9789400997448
Publisher: Springer Netherlands Publication: December 6, 2012
Imprint: Springer Language: English
Author:
ISBN: 9789400997448
Publisher: Springer Netherlands
Publication: December 6, 2012
Imprint: Springer
Language: English

Albumin is the most abundant serum protein produced by the liver. In clinical practice the serum level of albumin continues to be used as an important marker of the presence, progress or ofthe improvement of many diseases, even though it is the complex end result of synthesis, degradation a. nd distribution between intra- and extravascular space. The clinical history of albumin began as early as in 1837, when Ancell first recognized "albumen" and noted that this protein is needed for trans­ port functions, for maintaining fluidity of the vascular system and for the prevention of edema. However, the important physiological properties of serum proteins and their role in the regulation ofthe oncotic pressure were demonstrated later by the physiologist E. H. Starling in 1895. In 1917 the clinician A. A. Epstein first described the edema in patients with the nephro­ tic syndrome as being a result of a very low level of serum albumin. Al­ though the determination of serum albumin concentration became more popular after Howe in 1921 introduced the technique of separation of serum globulins from albumin by sodium sulfate, the first preparations of human serum albumin were made available for clinical use in only 1941 by the development of plasma fractionation by Cohn and his coworkers at Harvard Medical School.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Albumin is the most abundant serum protein produced by the liver. In clinical practice the serum level of albumin continues to be used as an important marker of the presence, progress or ofthe improvement of many diseases, even though it is the complex end result of synthesis, degradation a. nd distribution between intra- and extravascular space. The clinical history of albumin began as early as in 1837, when Ancell first recognized "albumen" and noted that this protein is needed for trans­ port functions, for maintaining fluidity of the vascular system and for the prevention of edema. However, the important physiological properties of serum proteins and their role in the regulation ofthe oncotic pressure were demonstrated later by the physiologist E. H. Starling in 1895. In 1917 the clinician A. A. Epstein first described the edema in patients with the nephro­ tic syndrome as being a result of a very low level of serum albumin. Al­ though the determination of serum albumin concentration became more popular after Howe in 1921 introduced the technique of separation of serum globulins from albumin by sodium sulfate, the first preparations of human serum albumin were made available for clinical use in only 1941 by the development of plasma fractionation by Cohn and his coworkers at Harvard Medical School.

More books from Springer Netherlands

Cover of the book Companion Modelling by
Cover of the book Acoustical Imaging by
Cover of the book Phenomenology of Time by
Cover of the book Biomanagement of Metal-Contaminated Soils by
Cover of the book Topics in Constraint-Based Grammar of Japanese by
Cover of the book Soil Formation by
Cover of the book Analog-to-Digital Conversion by
Cover of the book Glioma Signaling by
Cover of the book The Legal Status, Privileges and Immunities of the Specialized Agencies of the United Nations and Certain Other International Organizations by
Cover of the book Coral Reef Remote Sensing by
Cover of the book Gaswell Testing by
Cover of the book Fundamentals of Enzyme Engineering by
Cover of the book Semantical Essays by
Cover of the book Islamic Philosophy and Occidental Phenomenology in Dialogue by
Cover of the book Introduction to the Principles of Phonological Descriptions by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy