Comparative Biology of Aging

Nonfiction, Health & Well Being, Medical, Specialties, Geriatrics, Science & Nature, Science, Biological Sciences, Cytology
Cover of the book Comparative Biology of Aging by , Springer Netherlands
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9789048134656
Publisher: Springer Netherlands Publication: January 8, 2010
Imprint: Springer Language: English
Author:
ISBN: 9789048134656
Publisher: Springer Netherlands
Publication: January 8, 2010
Imprint: Springer
Language: English

determined by an inability to move in response to touch. C. elegans develop through four larval stages following hatching and prior to adulthood. Adult C. elegans are reproductive for about the rst week of adulthood followed by approximately two weeks of post-reproductive adulthood prior to death. Life span is most commonly measured in the laboratory by maintaining the worms on the surface of a nutrie- agar medium (Nematode Growth Medium, NGM) with E. coli OP50 as the bacterial food source (REF). Alternative culture conditions have been described in liquid media; however, these are not widely used for longevity studies. Longevity of the commonly used wild type C. elegans hermaphrodite (N2) varies ? from 16 to 23 days under standard laboratory conditions (20 C, NGM agar, E. coli OP50 food source). Life span can be increased by maintaining animals at lower ambient temperatures and shortened by raising the ambient temperature. Use of a killed bacterial food source, rather than live E. coli, increases lifespan by 2–4 days, and growth of adult animals in the absence of bacteria (axenic growth or bac- rial deprivation) increases median life span to 32–38 days [3, 23, 24]. Under both standard laboratory conditions and bacterial deprivation conditions, wild-derived C. elegans hermaphrodites exhibit longevity comparable to N2 animals [25].

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

determined by an inability to move in response to touch. C. elegans develop through four larval stages following hatching and prior to adulthood. Adult C. elegans are reproductive for about the rst week of adulthood followed by approximately two weeks of post-reproductive adulthood prior to death. Life span is most commonly measured in the laboratory by maintaining the worms on the surface of a nutrie- agar medium (Nematode Growth Medium, NGM) with E. coli OP50 as the bacterial food source (REF). Alternative culture conditions have been described in liquid media; however, these are not widely used for longevity studies. Longevity of the commonly used wild type C. elegans hermaphrodite (N2) varies ? from 16 to 23 days under standard laboratory conditions (20 C, NGM agar, E. coli OP50 food source). Life span can be increased by maintaining animals at lower ambient temperatures and shortened by raising the ambient temperature. Use of a killed bacterial food source, rather than live E. coli, increases lifespan by 2–4 days, and growth of adult animals in the absence of bacteria (axenic growth or bac- rial deprivation) increases median life span to 32–38 days [3, 23, 24]. Under both standard laboratory conditions and bacterial deprivation conditions, wild-derived C. elegans hermaphrodites exhibit longevity comparable to N2 animals [25].

More books from Springer Netherlands

Cover of the book Cognitive Aspects of Human-Computer Interaction for Geographic Information Systems by
Cover of the book Geographical Information Systems in Assessing Natural Hazards by
Cover of the book Kant's Critique of Pure Reason by
Cover of the book Structure and Properties of Liquid Crystals by
Cover of the book Lactoferrin and its Role in Wound Healing by
Cover of the book Relativism and Realism in Science by
Cover of the book Stem Cells and Cancer Stem Cells, Volume 8 by
Cover of the book The Body in Medical Thought and Practice by
Cover of the book History of Philosophy of Science by
Cover of the book BRST Symmetry and de Rham Cohomology by
Cover of the book Subsurface Solute Transport Models and Case Histories by
Cover of the book Evaluation of Continuing Education in the Health Professions by
Cover of the book Logistic Support of a Manned Underwater Production Complex by
Cover of the book The Global Age by
Cover of the book Ions in Water and Biophysical Implications by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy