Control and Prediction of Solid-State of Pharmaceuticals

Experimental and Computational Approaches

Nonfiction, Science & Nature, Science, Chemistry, Physical & Theoretical, Health & Well Being, Medical, Specialties, Pharmacy
Cover of the book Control and Prediction of Solid-State of Pharmaceuticals by Rajni Miglani Bhardwaj, Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Rajni Miglani Bhardwaj ISBN: 9783319275550
Publisher: Springer International Publishing Publication: February 2, 2016
Imprint: Springer Language: English
Author: Rajni Miglani Bhardwaj
ISBN: 9783319275550
Publisher: Springer International Publishing
Publication: February 2, 2016
Imprint: Springer
Language: English

This thesis investigates a range of experimental and computational approaches for the discovery of solid forms. Furthermore, we gain, as readers, a better understanding of the key factors underpinning solid-structure and diversity. A major part of this thesis highlights experimental work carried out on two structurally very similar compounds. Another important section involves looking at the influence of small changes in structure and substituents on solid-structure and diversity using computational tools including crystal structure prediction, PIXEL calculations, Xpac, Mercury and statistical modeling tools. In addition, the author presents a fast validated method for solid-state form screening using Raman microscopy on multi-well plates to explore the experimental crystallization space. This thesis illustrates an inexpensive, practical and accurate way to predict the crystallizability of organic compounds based on molecular structure alone, and additionally highlights the molecular factors that inhibit or promote crystallization.

 

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This thesis investigates a range of experimental and computational approaches for the discovery of solid forms. Furthermore, we gain, as readers, a better understanding of the key factors underpinning solid-structure and diversity. A major part of this thesis highlights experimental work carried out on two structurally very similar compounds. Another important section involves looking at the influence of small changes in structure and substituents on solid-structure and diversity using computational tools including crystal structure prediction, PIXEL calculations, Xpac, Mercury and statistical modeling tools. In addition, the author presents a fast validated method for solid-state form screening using Raman microscopy on multi-well plates to explore the experimental crystallization space. This thesis illustrates an inexpensive, practical and accurate way to predict the crystallizability of organic compounds based on molecular structure alone, and additionally highlights the molecular factors that inhibit or promote crystallization.

 

More books from Springer International Publishing

Cover of the book Classical Mechanics by Rajni Miglani Bhardwaj
Cover of the book The Police and International Human Rights Law by Rajni Miglani Bhardwaj
Cover of the book Security and Fault Tolerance in Internet of Things by Rajni Miglani Bhardwaj
Cover of the book Radio Frequency Modulation Made Easy by Rajni Miglani Bhardwaj
Cover of the book Software Engineering Aspects of Continuous Development and New Paradigms of Software Production and Deployment by Rajni Miglani Bhardwaj
Cover of the book Algal Biorefinery: An Integrated Approach by Rajni Miglani Bhardwaj
Cover of the book Thermo-Hydro-Mechanical-Chemical Processes in Fractured Porous Media: Modelling and Benchmarking by Rajni Miglani Bhardwaj
Cover of the book Sustainable City Management by Rajni Miglani Bhardwaj
Cover of the book Personal Injury and Damage Ascertainment under Civil Law by Rajni Miglani Bhardwaj
Cover of the book Cellular Automata and Discrete Complex Systems by Rajni Miglani Bhardwaj
Cover of the book Complex Plasmas by Rajni Miglani Bhardwaj
Cover of the book Single Molecular Machines and Motors by Rajni Miglani Bhardwaj
Cover of the book Synergies Between Knowledge Engineering and Software Engineering by Rajni Miglani Bhardwaj
Cover of the book Theory and Practice in the Bioarchaeology of Care by Rajni Miglani Bhardwaj
Cover of the book Norman Geras’s Political Thought from Marxism to Human Rights by Rajni Miglani Bhardwaj
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy