Correlation Force Spectroscopy for Single Molecule Measurements

Nonfiction, Science & Nature, Science, Physics, Spectrum Analysis, Biological Sciences, Molecular Physics
Cover of the book Correlation Force Spectroscopy for Single Molecule Measurements by Milad Radiom, Springer International Publishing
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Author: Milad Radiom ISBN: 9783319140483
Publisher: Springer International Publishing Publication: March 30, 2015
Imprint: Springer Language: English
Author: Milad Radiom
ISBN: 9783319140483
Publisher: Springer International Publishing
Publication: March 30, 2015
Imprint: Springer
Language: English

This thesis addresses the development of a new force spectroscopy tool, correlation force spectroscopy (CFS) for the measurement of the properties of very small volumes of material (molecular to µm3) at kHz-MHz frequency range. CFS measures the simultaneous thermal fluctuations of two closely-spaced atomic force microscopy (AFM) cantilevers.  CFS then calculates the cross-correlation in the thermal fluctuations that gives the mechanical properties of the matter that spans the gap of the two cantilevers. The book also discusses development of CFS, its advantages over AFM, and its application in single molecule force spectroscopy and micro-rheology.

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This thesis addresses the development of a new force spectroscopy tool, correlation force spectroscopy (CFS) for the measurement of the properties of very small volumes of material (molecular to µm3) at kHz-MHz frequency range. CFS measures the simultaneous thermal fluctuations of two closely-spaced atomic force microscopy (AFM) cantilevers.  CFS then calculates the cross-correlation in the thermal fluctuations that gives the mechanical properties of the matter that spans the gap of the two cantilevers. The book also discusses development of CFS, its advantages over AFM, and its application in single molecule force spectroscopy and micro-rheology.

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