Endocrine Therapies in Breast and Prostate Cancer

Nonfiction, Health & Well Being, Medical, Specialties, Oncology
Cover of the book Endocrine Therapies in Breast and Prostate Cancer by , Springer US
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781461317319
Publisher: Springer US Publication: December 6, 2012
Imprint: Springer Language: English
Author:
ISBN: 9781461317319
Publisher: Springer US
Publication: December 6, 2012
Imprint: Springer
Language: English

It has been recognized for many years that cancers originating in the breast and prostate gland are frequently 'endocrine-dependent. ' Traditional thera­ pies included surgical endocrine ablative procedures or pharmacologic hor­ mone administration, both designed to antagonize the stimulatory effects of sex steroid hormones. In the past decade, several new treatment strategies for these tumors have emerged from basic studies in reproductive biology and mechanisms of action of steroid hormones. In some instances, these new treatments have elimin­ ated or reduced the need for major surgical ablative procedures or for toxic hormone therapy. The clinical role for other new treatments has not yet been clearly defined, although exciting preliminary data from recent clinical trials are now available. Thus, an objective review of the current status of these new therapeutic approaches is of interest. In this volume we have attempted to provide an in-depth review of both basic and clinical research involving several new treatment strategies for breast and prostate cancer. The first three chapters summarize preclinical and clinical studies of the luteinizing hormone-releasing hormone analogues, which can be used effectively to induce 'medical castration. ' Chapters 4, 5, and 6 review the rationale and clinical use of the compounds known collec­ tively as the aromatase inhibitors, which can also be used to suppress sex steroid hormone levels. Antiestrogen mechanism of action and its clinical implications for the design of innovative treatment approaches is considered in chapters 7 and 8.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

It has been recognized for many years that cancers originating in the breast and prostate gland are frequently 'endocrine-dependent. ' Traditional thera­ pies included surgical endocrine ablative procedures or pharmacologic hor­ mone administration, both designed to antagonize the stimulatory effects of sex steroid hormones. In the past decade, several new treatment strategies for these tumors have emerged from basic studies in reproductive biology and mechanisms of action of steroid hormones. In some instances, these new treatments have elimin­ ated or reduced the need for major surgical ablative procedures or for toxic hormone therapy. The clinical role for other new treatments has not yet been clearly defined, although exciting preliminary data from recent clinical trials are now available. Thus, an objective review of the current status of these new therapeutic approaches is of interest. In this volume we have attempted to provide an in-depth review of both basic and clinical research involving several new treatment strategies for breast and prostate cancer. The first three chapters summarize preclinical and clinical studies of the luteinizing hormone-releasing hormone analogues, which can be used effectively to induce 'medical castration. ' Chapters 4, 5, and 6 review the rationale and clinical use of the compounds known collec­ tively as the aromatase inhibitors, which can also be used to suppress sex steroid hormone levels. Antiestrogen mechanism of action and its clinical implications for the design of innovative treatment approaches is considered in chapters 7 and 8.

More books from Springer US

Cover of the book Applied Chemistry by
Cover of the book Mechanisms of Lymphocyte Activation and Immune Regulation VIII by
Cover of the book Financial Modernization and Regulation by
Cover of the book Ultrasound by
Cover of the book Handbook of Nonverbal Assessment by
Cover of the book Thin Film Metal-Oxides by
Cover of the book The Cancer Patient and Supportive Care by
Cover of the book Instrumental Analysis in the Biological Sciences by
Cover of the book Reviews of Environmental Contamination and Toxicology 201 by
Cover of the book Clinical Neuropsychological Assessment by
Cover of the book Basophil and Mast Cell Degranulation and Recovery by
Cover of the book The Annotated Bibliography of International Programme Evaluation by
Cover of the book Fundamentals of Cybernetics by
Cover of the book Mechanisms of Cerebral Hypoxia and Stroke by
Cover of the book The Collected Works of L.S. Vygotsky by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy