Handbook of Neuroemergency Clinical Trials

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology, Science & Nature, Science, Biological Sciences
Cover of the book Handbook of Neuroemergency Clinical Trials by , Elsevier Science
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Author: ISBN: 9780080454351
Publisher: Elsevier Science Publication: January 18, 2006
Imprint: Academic Press Language: English
Author:
ISBN: 9780080454351
Publisher: Elsevier Science
Publication: January 18, 2006
Imprint: Academic Press
Language: English

During the 1990’s, scientific advances in understanding the mechanisms and pathophysiology of acute central nervous system injury were offset by a history of disappointing results from Phase III clinical trials of novel neuroprotective drugs. Numerous novel compounds were “tested,” and seemingly fell by the wayside. This book is intended to focus on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. The authors explore the issues facing research in this area and the strategies that might lead to future success in this critical area of unmet medical need. It represents a compendium of information gained from over 20 years of clinical trial experience in areas of acute neurology and neurosurgery. From the knowledge of clinical assessment using standardized tools, to the intricate design of difficult hyper-acute neuroemergencies trials, the reader will benefit from the authors’ perspectives.

* Presents new perspectives on acute neuroemergency clinical trials
* Includes insights from clinical pharmacology and industry perspectives
* Discusses historical lessons learned from early and recent trials in acute neuroscience populations

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

During the 1990’s, scientific advances in understanding the mechanisms and pathophysiology of acute central nervous system injury were offset by a history of disappointing results from Phase III clinical trials of novel neuroprotective drugs. Numerous novel compounds were “tested,” and seemingly fell by the wayside. This book is intended to focus on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. The authors explore the issues facing research in this area and the strategies that might lead to future success in this critical area of unmet medical need. It represents a compendium of information gained from over 20 years of clinical trial experience in areas of acute neurology and neurosurgery. From the knowledge of clinical assessment using standardized tools, to the intricate design of difficult hyper-acute neuroemergencies trials, the reader will benefit from the authors’ perspectives.

* Presents new perspectives on acute neuroemergency clinical trials
* Includes insights from clinical pharmacology and industry perspectives
* Discusses historical lessons learned from early and recent trials in acute neuroscience populations

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