Hydroxy-Pyridones as Antifungal Agents with Special Emphasis on Onychomycosis

Nonfiction, Health & Well Being, Medical, Medical Science, Microbiology, Pharmacology
Cover of the book Hydroxy-Pyridones as Antifungal Agents with Special Emphasis on Onychomycosis by , Springer Berlin Heidelberg
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Author: ISBN: 9783642584015
Publisher: Springer Berlin Heidelberg Publication: November 11, 2013
Imprint: Springer Language: English
Author:
ISBN: 9783642584015
Publisher: Springer Berlin Heidelberg
Publication: November 11, 2013
Imprint: Springer
Language: English

This book summarizes the results of two symposia held on hydroxy-pyridones as antifungal agents organized on the occasion of the International Summit on Cutaneous Antifungal Therapy 1996 in Vancouver and the 19th World Congress of Dermatology 1997 in Sydney. Some of the papers deal with the basic mechanisms of action and how these translate into product features, e.g. activity spectrum. Other papers describe the unique properties of hydroxy-pyridones, such as high penetration into and through keratinic tissues or their activity as dual inhibitor on 5-lipoxygenase and cyclooxygenase which leads to a remarkable antiinflammatory effect. Last but not least various accounts are given which show how this unique product profile aids the treatment of various fungal diseases, especially onychomycosis.

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This book summarizes the results of two symposia held on hydroxy-pyridones as antifungal agents organized on the occasion of the International Summit on Cutaneous Antifungal Therapy 1996 in Vancouver and the 19th World Congress of Dermatology 1997 in Sydney. Some of the papers deal with the basic mechanisms of action and how these translate into product features, e.g. activity spectrum. Other papers describe the unique properties of hydroxy-pyridones, such as high penetration into and through keratinic tissues or their activity as dual inhibitor on 5-lipoxygenase and cyclooxygenase which leads to a remarkable antiinflammatory effect. Last but not least various accounts are given which show how this unique product profile aids the treatment of various fungal diseases, especially onychomycosis.

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