Immunochemistry Of The Extracellular Matrix

Volume 2

Nonfiction, Science & Nature, Science, Biological Sciences, Cytology
Cover of the book Immunochemistry Of The Extracellular Matrix by Furthmayr, CRC Press
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Author: Furthmayr ISBN: 9781351090322
Publisher: CRC Press Publication: January 18, 2018
Imprint: CRC Press Language: English
Author: Furthmayr
ISBN: 9781351090322
Publisher: CRC Press
Publication: January 18, 2018
Imprint: CRC Press
Language: English

The main purpose of the two volumes on Immunochemistry of the Extracellular Matrix is to describe state of the art methods, which have been proven to provide antibody reagents of defined specificity to collagens as well as other glycoproteins found in association within connective tissue. The isolation and purification of collagens, procollagens, and related connective tissue proteins are described for several tissues, tissue culture cells and species. Immunization with these collagens in laboratory animals yields antibodies with different characteristic specificities: to the procollagen extension fragments, the non-helical segments of the a-chains, to helical and denatured determinants.

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The main purpose of the two volumes on Immunochemistry of the Extracellular Matrix is to describe state of the art methods, which have been proven to provide antibody reagents of defined specificity to collagens as well as other glycoproteins found in association within connective tissue. The isolation and purification of collagens, procollagens, and related connective tissue proteins are described for several tissues, tissue culture cells and species. Immunization with these collagens in laboratory animals yields antibodies with different characteristic specificities: to the procollagen extension fragments, the non-helical segments of the a-chains, to helical and denatured determinants.

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