Immunotherapy of Hepatocellular Carcinoma

Nonfiction, Health & Well Being, Medical, Reference, Research
Cover of the book Immunotherapy of Hepatocellular Carcinoma by , Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783319649580
Publisher: Springer International Publishing Publication: October 4, 2017
Imprint: Springer Language: English
Author:
ISBN: 9783319649580
Publisher: Springer International Publishing
Publication: October 4, 2017
Imprint: Springer
Language: English

In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials.   

Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer.

Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials.   

Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer.

Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.

More books from Springer International Publishing

Cover of the book Spline and Spline Wavelet Methods with Applications to Signal and Image Processing by
Cover of the book Advances in Robot Kinematics 2018 by
Cover of the book Women in Numbers Europe II by
Cover of the book Marathon Running: Physiology, Psychology, Nutrition and Training Aspects by
Cover of the book Cloud Computing and Security by
Cover of the book The Mobile Learning Voyage - From Small Ripples to Massive Open Waters by
Cover of the book A Short Course on Topological Insulators by
Cover of the book Separably Injective Banach Spaces by
Cover of the book Simulating Social Complexity by
Cover of the book Retail Crime by
Cover of the book Planning Support Science for Smarter Urban Futures by
Cover of the book Interface Fracture and Delaminations in Composite Materials by
Cover of the book The Making of Catalan Linguistic Identity in Medieval and Early Modern Times by
Cover of the book US Environmental Policy in Action by
Cover of the book Smart Education and Smart e-Learning by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy