In vivo Models for Drug Discovery

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology
Cover of the book In vivo Models for Drug Discovery by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers, Wiley
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ISBN: 9783527679362
Publisher: Wiley Publication: July 31, 2014
Imprint: Wiley-VCH Language: English
Author: Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
ISBN: 9783527679362
Publisher: Wiley
Publication: July 31, 2014
Imprint: Wiley-VCH
Language: English

This one-stop reference is the first to present the complete picture -- covering all relevant organisms, from single cells to mammals, as well as all major disease areas, including neurological disorders, cancer and infectious diseases.
Addressing the needs of the pharmaceutical industry, this unique handbook adopts a broad perspective on the use of animals in the early part of the drug development process, including regulatory rules and limitations, as well as numerous examples from real-life drug development projects.
After a general introduction to the topic, the expert contributors from research-driven pharmaceutical companies discuss the basic considerations of using animal models, including ethical issues. The main part of the book systematically surveys the most important disease areas for current drug development, from cardiovascular to endocrine disorders, and from infectious to neurological diseases. For each area, the availability of animal models for target validation, hit finding and lead profiling is reviewed, backed by numerous examples of both successes and failures among the use of animal models. The whole is rounded off with a discussion of perspectives and challenges.
Key knowledge for drug researchers in industry as well as academia.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This one-stop reference is the first to present the complete picture -- covering all relevant organisms, from single cells to mammals, as well as all major disease areas, including neurological disorders, cancer and infectious diseases.
Addressing the needs of the pharmaceutical industry, this unique handbook adopts a broad perspective on the use of animals in the early part of the drug development process, including regulatory rules and limitations, as well as numerous examples from real-life drug development projects.
After a general introduction to the topic, the expert contributors from research-driven pharmaceutical companies discuss the basic considerations of using animal models, including ethical issues. The main part of the book systematically surveys the most important disease areas for current drug development, from cardiovascular to endocrine disorders, and from infectious to neurological diseases. For each area, the availability of animal models for target validation, hit finding and lead profiling is reviewed, backed by numerous examples of both successes and failures among the use of animal models. The whole is rounded off with a discussion of perspectives and challenges.
Key knowledge for drug researchers in industry as well as academia.

More books from Wiley

Cover of the book Statistical and Machine Learning Approaches for Network Analysis by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Achieving Excellence in Fundraising by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Scale Invariance by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Non-volatile Memories by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Polypropylene-Based Biocomposites and Bionanocomposites by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Issues in Distance Education by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Math Wise! Over 100 Hands-On Activities that Promote Real Math Understanding, Grades K-8 by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Conservation Biology by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Panel Data Analysis using EViews by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Macrocyclic and Supramolecular Chemistry by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Handbook of Metathesis, Volume 2 by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Chemometrics by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Governmental Accounting Made Easy by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Teach Yourself VISUALLY WordPress by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Cover of the book Managed Futures for Institutional Investors by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy