Insulin Resistance - ECAB

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Endocrinology & Metabolism
Cover of the book Insulin Resistance - ECAB by Gita Ganguly Mukherjee, Elsevier Health Sciences APAC
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Gita Ganguly Mukherjee ISBN: 9788131232217
Publisher: Elsevier Health Sciences APAC Publication: October 26, 2010
Imprint: Elsevier India Language: English
Author: Gita Ganguly Mukherjee
ISBN: 9788131232217
Publisher: Elsevier Health Sciences APAC
Publication: October 26, 2010
Imprint: Elsevier India
Language: English
The insulin resistance syndrome can be defined as insulin resistance, compensatory hyperinsulinemia, and their associated co-morbidities. Clinically, the term insulin resistance syndrome describes a constellation of abnormalities such as obesity, hypertension, dyslipidemia, type 2 diabetes/hyperglycemia, and coronary artery disease.

Insulin is responsible for glucose uptake into the body cells and tissues. The response of the cells to insulin varies from individual to individual. In some individuals, the tissue response to insulin may be diminished. This means that even with adequate levels of insulin, the glucose uptake into the cells and tissues is not optimal. This results in a compensatory over-secretion of insulin from the pancreas. The

persistence of high levels of insulin in the blood or hyperinsulinemia is thought to be responsible for some of the abnormalities associated with this condition. However, the exact causal association of the condition with these disorders and the pathophysiology of their evolution are unclear.

The most common underlying mechanism proposed is increased free fatty acids from abdominal fat in individuals with central obesity. This leads to deranged insulin signaling, reduced muscular glucose uptake, increased triglyceride synthesis, and hepatic gluconeogenesis. A genetic basis of the disease as well as several other factors such as tumor necrosis factor-a, adiponectin, leptin, Interleukin-6, and some adipokines have also been implicated.

Insulin resistance syndrome is of clinical significance because of its association with potentially debilitating conditions that contribute to long-term morbidity and even mortality of the individual. People with insulin resistance syndrome are at an increased risk of developing type 2 diabetes, hypertension, dyslipidemia, myocardial infarction, polycystic ovarian disease, and fatty liver.

In this book, we have tried to collate the experiences of the pioneers of this field on the subject and provide the reader a comprehensive view on the topic along with practical management points, which we are sure will benefit the physicians in their clinical practice. The contributors have focused on the condition as is prevalent in our subcontinent and have tried to give an insight on the issues pertaining to the same with a topical flavor.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
The insulin resistance syndrome can be defined as insulin resistance, compensatory hyperinsulinemia, and their associated co-morbidities. Clinically, the term insulin resistance syndrome describes a constellation of abnormalities such as obesity, hypertension, dyslipidemia, type 2 diabetes/hyperglycemia, and coronary artery disease.

Insulin is responsible for glucose uptake into the body cells and tissues. The response of the cells to insulin varies from individual to individual. In some individuals, the tissue response to insulin may be diminished. This means that even with adequate levels of insulin, the glucose uptake into the cells and tissues is not optimal. This results in a compensatory over-secretion of insulin from the pancreas. The

persistence of high levels of insulin in the blood or hyperinsulinemia is thought to be responsible for some of the abnormalities associated with this condition. However, the exact causal association of the condition with these disorders and the pathophysiology of their evolution are unclear.

The most common underlying mechanism proposed is increased free fatty acids from abdominal fat in individuals with central obesity. This leads to deranged insulin signaling, reduced muscular glucose uptake, increased triglyceride synthesis, and hepatic gluconeogenesis. A genetic basis of the disease as well as several other factors such as tumor necrosis factor-a, adiponectin, leptin, Interleukin-6, and some adipokines have also been implicated.

Insulin resistance syndrome is of clinical significance because of its association with potentially debilitating conditions that contribute to long-term morbidity and even mortality of the individual. People with insulin resistance syndrome are at an increased risk of developing type 2 diabetes, hypertension, dyslipidemia, myocardial infarction, polycystic ovarian disease, and fatty liver.

In this book, we have tried to collate the experiences of the pioneers of this field on the subject and provide the reader a comprehensive view on the topic along with practical management points, which we are sure will benefit the physicians in their clinical practice. The contributors have focused on the condition as is prevalent in our subcontinent and have tried to give an insight on the issues pertaining to the same with a topical flavor.

More books from Endocrinology & Metabolism

Cover of the book Cushing's Disease by Gita Ganguly Mukherjee
Cover of the book Malignant Tumors of the Thyroid by Gita Ganguly Mukherjee
Cover of the book The Pineal Gland and Cancer by Gita Ganguly Mukherjee
Cover of the book Oxford Handbook of Endocrinology and Diabetes by Gita Ganguly Mukherjee
Cover of the book Motivational Interviewing in Diabetes Care by Gita Ganguly Mukherjee
Cover of the book Endocrine Oncology by Gita Ganguly Mukherjee
Cover of the book Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity by Gita Ganguly Mukherjee
Cover of the book Recent Advances in Transthyretin Evolution, Structure and Biological Functions by Gita Ganguly Mukherjee
Cover of the book Calcium-Sensing Receptor by Gita Ganguly Mukherjee
Cover of the book Clinical Hepatology by Gita Ganguly Mukherjee
Cover of the book The Hormone Reset Diet by Gita Ganguly Mukherjee
Cover of the book Paget’s Disease of Bone by Gita Ganguly Mukherjee
Cover of the book Immunoendocrinology: Scientific and Clinical Aspects by Gita Ganguly Mukherjee
Cover of the book Menopause by Gita Ganguly Mukherjee
Cover of the book Lipids and Women’s Health by Gita Ganguly Mukherjee
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy