Kinase Inhibitor Drugs

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology
Cover of the book Kinase Inhibitor Drugs by Rongshi Li, Jeffrey A. Stafford, Wiley
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Rongshi Li, Jeffrey A. Stafford ISBN: 9781118210901
Publisher: Wiley Publication: September 20, 2011
Imprint: Wiley Language: English
Author: Rongshi Li, Jeffrey A. Stafford
ISBN: 9781118210901
Publisher: Wiley
Publication: September 20, 2011
Imprint: Wiley
Language: English

A comprehensive resource on case studies of marketed kinase drugs and promising drug trials

Since the discovery of protein kinase activity in 1954, the field of protein kinase drug discovery has advanced dramatically. With the ongoing clinical success of the Bcr-Abl kinase inhibitor Gleevec in the treatment of chronic myelogenous leukemia and seven additional marketed kinase inhibitor drugs, researchers have compelling evidence that kinase inhibitors can be highly efficacious in the treatment of diseases caused by aberrant activity of protein kinase. Currently more than 100 protein kinase inhibitors are in clinical development.

In one comprehensive volume, the editors, Dr. Rongshi Li and Dr. Jeffrey Stafford, present timely and important case studies of marketed kinase drugs and several of the most advanced kinase inhibitors in clinical trials. Kinase Inhibitor Drugs includes:

  • Case studies from leading investigators and experts in the field that provide firsthand accounts of kinase inhibitor discovery
  • Current thinking on kinase structure, biochemistry, and signal transduction pathways
  • Information on state-of-the-art technologies and tools such as structure-based and fragment-based drug discovery
  • A lineup of clinical-phase growth factor receptor inhibitors
  • Inhibitors of cell cycle kinases
  • The discovery of allosteric inhibitors of MEK kinase
  • Information on pharmacogenomics and its application to kinase inhibitor clinical development
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

A comprehensive resource on case studies of marketed kinase drugs and promising drug trials

Since the discovery of protein kinase activity in 1954, the field of protein kinase drug discovery has advanced dramatically. With the ongoing clinical success of the Bcr-Abl kinase inhibitor Gleevec in the treatment of chronic myelogenous leukemia and seven additional marketed kinase inhibitor drugs, researchers have compelling evidence that kinase inhibitors can be highly efficacious in the treatment of diseases caused by aberrant activity of protein kinase. Currently more than 100 protein kinase inhibitors are in clinical development.

In one comprehensive volume, the editors, Dr. Rongshi Li and Dr. Jeffrey Stafford, present timely and important case studies of marketed kinase drugs and several of the most advanced kinase inhibitors in clinical trials. Kinase Inhibitor Drugs includes:

More books from Wiley

Cover of the book Biomaterials from Nature for Advanced Devices and Therapies by Rongshi Li, Jeffrey A. Stafford
Cover of the book Tissue Engineering for Artificial Organs by Rongshi Li, Jeffrey A. Stafford
Cover of the book Distance and E-learning in Transition by Rongshi Li, Jeffrey A. Stafford
Cover of the book Psoriasis by Rongshi Li, Jeffrey A. Stafford
Cover of the book Mobile Satellite Communications Handbook by Rongshi Li, Jeffrey A. Stafford
Cover of the book Infrastructure Investing by Rongshi Li, Jeffrey A. Stafford
Cover of the book Microgrids by Rongshi Li, Jeffrey A. Stafford
Cover of the book Leading for the Future: Alignment of AACC Competencies with Practice by Rongshi Li, Jeffrey A. Stafford
Cover of the book Astrobiology by Rongshi Li, Jeffrey A. Stafford
Cover of the book Proteins by Rongshi Li, Jeffrey A. Stafford
Cover of the book A Companion to Chinese Archaeology by Rongshi Li, Jeffrey A. Stafford
Cover of the book Guide to Canine and Feline Electrocardiography by Rongshi Li, Jeffrey A. Stafford
Cover of the book Drawing in the Digital Age by Rongshi Li, Jeffrey A. Stafford
Cover of the book QGIS and Generic Tools by Rongshi Li, Jeffrey A. Stafford
Cover of the book Financial Jiu-Jitsu by Rongshi Li, Jeffrey A. Stafford
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy