Linkage Thermodynamics of Macromolecular Interactions

Nonfiction, Science & Nature, Science, Other Sciences, Molecular Biology, Biological Sciences, Biochemistry
Cover of the book Linkage Thermodynamics of Macromolecular Interactions by Frederic M. Richards, David S. Eisenberg, Peter S. Kim, Enrico Di Cera, Elsevier Science
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Author: Frederic M. Richards, David S. Eisenberg, Peter S. Kim, Enrico Di Cera ISBN: 9780080582245
Publisher: Elsevier Science Publication: June 24, 1998
Imprint: Language: English
Author: Frederic M. Richards, David S. Eisenberg, Peter S. Kim, Enrico Di Cera
ISBN: 9780080582245
Publisher: Elsevier Science
Publication: June 24, 1998
Imprint:
Language: English
This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-the-art of this important field and on new developments of the original theory. Among the topics covered in this volume are electrostatic contributions to molecular free energies in solution; site-specific analysis of mutational effects in proteins; allosteric transitions of the acetylcholine receptor; and deciphering the molecular code of hemoglobin allostery.
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This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-the-art of this important field and on new developments of the original theory. Among the topics covered in this volume are electrostatic contributions to molecular free energies in solution; site-specific analysis of mutational effects in proteins; allosteric transitions of the acetylcholine receptor; and deciphering the molecular code of hemoglobin allostery.

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