Molecular Aspects of Early Development

Kids, Natural World, Nonfiction, Reference & Language, Education & Teaching, Science & Nature, Science
Cover of the book Molecular Aspects of Early Development by , Springer US
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781468446289
Publisher: Springer US Publication: December 6, 2012
Imprint: Springer Language: English
Author:
ISBN: 9781468446289
Publisher: Springer US
Publication: December 6, 2012
Imprint: Springer
Language: English

The early embryo has emerged as the focal point for analysis of the regulation of gene expression for several reasons. First, the fact that embryogenesis is under genetic control has been appreciated from the earliest days of classical embryology. When experimental techniques became available it was therefore logical that they should be applied to the embryo. With each new advance in methodology, interest in embryonic gene expression studies has increased. Second, many embryos offer unique opportunities for the investigation of specific aspects of the regulation of gene expression. Several phenomena--eg. , control of translation--can be very conveniently studied in a variety of marine invertebrate embryos. Those embryos contain large stores of maternally inherited mRNA which are translated in a highly ordered fashion during specific stages of post fertilization development. Marine invertebrate eggs can be conveniently artifically inseminated and labeled with radioactive precursors. Their analysis is leading to important insights into the mechanisms which regulate gene expression at post-transcriptional levels. Third, recent advances in both transmission and recombinant DNA genetics, especially in organisms such as Drosophila, are providing special opportunities for the analysis of regulatory mechanisms which operate at the level of the genome. Specific genes have been identified, isolated, and--in some instances--sequenced. The opportunity is now available to study the regulation of the expression of single genes in a vertical fashion--from the primary sequence of the gene to the tissues and organs which are the products of morphogenesis.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

The early embryo has emerged as the focal point for analysis of the regulation of gene expression for several reasons. First, the fact that embryogenesis is under genetic control has been appreciated from the earliest days of classical embryology. When experimental techniques became available it was therefore logical that they should be applied to the embryo. With each new advance in methodology, interest in embryonic gene expression studies has increased. Second, many embryos offer unique opportunities for the investigation of specific aspects of the regulation of gene expression. Several phenomena--eg. , control of translation--can be very conveniently studied in a variety of marine invertebrate embryos. Those embryos contain large stores of maternally inherited mRNA which are translated in a highly ordered fashion during specific stages of post fertilization development. Marine invertebrate eggs can be conveniently artifically inseminated and labeled with radioactive precursors. Their analysis is leading to important insights into the mechanisms which regulate gene expression at post-transcriptional levels. Third, recent advances in both transmission and recombinant DNA genetics, especially in organisms such as Drosophila, are providing special opportunities for the analysis of regulatory mechanisms which operate at the level of the genome. Specific genes have been identified, isolated, and--in some instances--sequenced. The opportunity is now available to study the regulation of the expression of single genes in a vertical fashion--from the primary sequence of the gene to the tissues and organs which are the products of morphogenesis.

More books from Springer US

Cover of the book The Postmortem Brain in Psychiatric Research by
Cover of the book Single Family Selective Rehabilitation by
Cover of the book Frontiers in Thyroidology by
Cover of the book Perspectives in Primate Biology by
Cover of the book Molecular Targeting and Signal Transduction by
Cover of the book Breakdown of Speech by
Cover of the book The Exploitation of Plant Resources in Ancient Africa by
Cover of the book Superconducting Electron-Optic Devices by
Cover of the book Successful Prevention Programs for Children and Adolescents by
Cover of the book Villagers of the Maros by
Cover of the book Furthering Talk by
Cover of the book Reliability Assessment of Large Electric Power Systems by
Cover of the book Foreign Aid in the Twenty-First Century by
Cover of the book Urological Research by
Cover of the book People and the Environment by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy