Neocortical Grafting to Newborn and Adult Rats: Developmental, Anatomical and Functional Aspects

Nonfiction, Science & Nature, Science, Other Sciences, Molecular Biology, Health & Well Being, Medical, Specialties, Internal Medicine, Neuroscience
Cover of the book Neocortical Grafting to Newborn and Adult Rats: Developmental, Anatomical and Functional Aspects by Afsaneh Gaillard, Frederic Gaillard, Michel Roger, Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Afsaneh Gaillard, Frederic Gaillard, Michel Roger ISBN: 9783642721793
Publisher: Springer Berlin Heidelberg Publication: March 12, 2013
Imprint: Springer Language: English
Author: Afsaneh Gaillard, Frederic Gaillard, Michel Roger
ISBN: 9783642721793
Publisher: Springer Berlin Heidelberg
Publication: March 12, 2013
Imprint: Springer
Language: English

The first experiments with neural transplantation into the brain (for a review, see Bjorklund and Stenevi 1985) were reported at the end of the last century by Thompson (1890), who took cortical tissue from adult cats and implanted the tissue pieces into the neocortex of adult dogs. The neurons did not survive, but the transplanted mass did not disintegrate entirely. Successful graft­ ing into the brain was reported later by Ranson (1909), who implanted spinal ganglia into the cerebral cortex of developing rats, and by Dunn (1917), who reported survival of implanted neonatal cortex into the cortex of newborn recipients. Another important step was made by Le Gros Clark (1940) who reported that, in the rabbit, embryonic (E) cortical tissue could be successfully grafted into the cortex of young recipients. Ex­ periments by Wallace and Das (1982), and Bjorklund and Stenevi (1984), showing behavioral effects of grafts, subsequently stimu­ lated a growing interest in neurotransplantation research. Intrac­ erebral grafting is now considered a powerful tool for addressing fundamental questions about development, regenerative, or re­ storative phenomena in the central nervous system (CNS) and is a potential therapy for neurodegenerative diseases.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

The first experiments with neural transplantation into the brain (for a review, see Bjorklund and Stenevi 1985) were reported at the end of the last century by Thompson (1890), who took cortical tissue from adult cats and implanted the tissue pieces into the neocortex of adult dogs. The neurons did not survive, but the transplanted mass did not disintegrate entirely. Successful graft­ ing into the brain was reported later by Ranson (1909), who implanted spinal ganglia into the cerebral cortex of developing rats, and by Dunn (1917), who reported survival of implanted neonatal cortex into the cortex of newborn recipients. Another important step was made by Le Gros Clark (1940) who reported that, in the rabbit, embryonic (E) cortical tissue could be successfully grafted into the cortex of young recipients. Ex­ periments by Wallace and Das (1982), and Bjorklund and Stenevi (1984), showing behavioral effects of grafts, subsequently stimu­ lated a growing interest in neurotransplantation research. Intrac­ erebral grafting is now considered a powerful tool for addressing fundamental questions about development, regenerative, or re­ storative phenomena in the central nervous system (CNS) and is a potential therapy for neurodegenerative diseases.

More books from Springer Berlin Heidelberg

Cover of the book Aufzüge und Fahrtreppen by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book In-Memory Data Management by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book GPS for Geodesy by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book Cognitive Computing by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book Complex Macromolecular Systems II by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book Nature and Significance of the Recent Carbonate Mound Record by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book Long Term Economic Development by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book Genetik by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book Pocket Guide Anästhesie by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book Natural Disasters and Sustainable Development by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book Space-Time Reference Systems by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book Transactions on Aspect-Oriented Software Development XII by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book Bacteria in Agrobiology: Plant Nutrient Management by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book Open Education: from OERs to MOOCs by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
Cover of the book Conducting Polymers by Afsaneh Gaillard, Frederic Gaillard, Michel Roger
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy