Author: | Alessandra Pescatore, Matilde Valeria Ursini, Francesca Fusco, Jérémie Gautheron, Anna Senegas, Gilles Courtois | ISBN: | 9783319258508 |
Publisher: | Springer International Publishing | Publication: | December 29, 2015 |
Imprint: | Springer | Language: | English |
Author: | Alessandra Pescatore, Matilde Valeria Ursini, Francesca Fusco, Jérémie Gautheron, Anna Senegas, Gilles Courtois |
ISBN: | 9783319258508 |
Publisher: | Springer International Publishing |
Publication: | December 29, 2015 |
Imprint: | Springer |
Language: | English |
This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.
This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.