NMR Spectroscopy in Pharmaceutical Analysis

Nonfiction, Science & Nature, Science, Physics, Spectrum Analysis, Chemistry, General Chemistry
Cover of the book NMR Spectroscopy in Pharmaceutical Analysis by Ulrike Holzgrabe, Elsevier Science
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Ulrike Holzgrabe ISBN: 9780080558196
Publisher: Elsevier Science Publication: August 22, 2008
Imprint: Elsevier Science Language: English
Author: Ulrike Holzgrabe
ISBN: 9780080558196
Publisher: Elsevier Science
Publication: August 22, 2008
Imprint: Elsevier Science
Language: English

For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized.
Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis.
Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples.

  • Combines theory, techniques, and concrete applications—all of which closely resemble the laboratory experience
  • Considers international pharmacopoeias, addressing the concern for licensing
  • Features the work of academics and researchers, appealing to a broad readership
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized.
Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis.
Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples.

More books from Elsevier Science

Cover of the book Linear Models by Ulrike Holzgrabe
Cover of the book Computational Quantum Chemistry II - The Group Theory Calculator by Ulrike Holzgrabe
Cover of the book Analysis of Turbulent Flows with Computer Programs by Ulrike Holzgrabe
Cover of the book Amorphous Chalcogenides by Ulrike Holzgrabe
Cover of the book Unleashing Web 2.0 by Ulrike Holzgrabe
Cover of the book Advances in the Study of Behavior by Ulrike Holzgrabe
Cover of the book Advances in Imaging and Electron Physics by Ulrike Holzgrabe
Cover of the book Congenital Heart Disease and Neurodevelopment by Ulrike Holzgrabe
Cover of the book Adenosine Receptors in Neurology and Psychiatry by Ulrike Holzgrabe
Cover of the book Seldin and Giebisch's The Kidney by Ulrike Holzgrabe
Cover of the book Game Theory and Learning for Wireless Networks by Ulrike Holzgrabe
Cover of the book Handbook of Empirical Corporate Finance SET by Ulrike Holzgrabe
Cover of the book Fashion Supply Chain Management Using Radio Frequency Identification (RFID) Technologies by Ulrike Holzgrabe
Cover of the book Methods in Consumer Research, Volume 1 by Ulrike Holzgrabe
Cover of the book Dendritic Cells by Ulrike Holzgrabe
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy