Oral Bioavailability Assessment

Basics and Strategies for Drug Discovery and Development

Nonfiction, Science & Nature, Science, Chemistry, Analytic, Health & Well Being, Medical, Medical Science, Pharmacology
Cover of the book Oral Bioavailability Assessment by Ayman F. El-Kattan, Mike S. Lee, Wiley
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Ayman F. El-Kattan, Mike S. Lee ISBN: 9781118916933
Publisher: Wiley Publication: May 15, 2017
Imprint: Wiley Language: English
Author: Ayman F. El-Kattan, Mike S. Lee
ISBN: 9781118916933
Publisher: Wiley
Publication: May 15, 2017
Imprint: Wiley
Language: English

Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability – one of the most significant hurdles in drug discovery and development.

• Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability
• Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development
• Explains how preclinical animal models – used in preclinical testing – and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development
• Includes chapters about pharmacokinetic modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS)
• Has tutorials for applying strategies to medicinal chemistry practices of drug discovery/development

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability – one of the most significant hurdles in drug discovery and development.

• Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability
• Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development
• Explains how preclinical animal models – used in preclinical testing – and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development
• Includes chapters about pharmacokinetic modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS)
• Has tutorials for applying strategies to medicinal chemistry practices of drug discovery/development

More books from Wiley

Cover of the book A Companion to Rock Art by Ayman F. El-Kattan, Mike S. Lee
Cover of the book The HPLC-MS Handbook for Practitioners by Ayman F. El-Kattan, Mike S. Lee
Cover of the book The Intuitive Compass by Ayman F. El-Kattan, Mike S. Lee
Cover of the book Zero Limits by Ayman F. El-Kattan, Mike S. Lee
Cover of the book Progress in Inorganic Chemistry by Ayman F. El-Kattan, Mike S. Lee
Cover of the book Introduction to Pragmatics by Ayman F. El-Kattan, Mike S. Lee
Cover of the book The Lightest Metals by Ayman F. El-Kattan, Mike S. Lee
Cover of the book RF / Microwave Circuit Design for Wireless Applications by Ayman F. El-Kattan, Mike S. Lee
Cover of the book Measuring the Networked Nonprofit by Ayman F. El-Kattan, Mike S. Lee
Cover of the book White Dwarf Atmospheres and Circumstellar Environments by Ayman F. El-Kattan, Mike S. Lee
Cover of the book Structural Timber Design to Eurocode 5 by Ayman F. El-Kattan, Mike S. Lee
Cover of the book The Hands-on Guide to Diabetes Care in Hospital by Ayman F. El-Kattan, Mike S. Lee
Cover of the book Database Development For Dummies by Ayman F. El-Kattan, Mike S. Lee
Cover of the book Transition to Renewable Energy Systems by Ayman F. El-Kattan, Mike S. Lee
Cover of the book Advances in Bioceramics and Porous Ceramics VII by Ayman F. El-Kattan, Mike S. Lee
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy