Organolithiums: Selectivity for Synthesis

Nonfiction, Science & Nature, Science, Chemistry, Organic, General Chemistry, Technology
Cover of the book Organolithiums: Selectivity for Synthesis by Jonathan Clayden, Elsevier Science
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Jonathan Clayden ISBN: 9780080538167
Publisher: Elsevier Science Publication: July 12, 2002
Imprint: Pergamon Language: English
Author: Jonathan Clayden
ISBN: 9780080538167
Publisher: Elsevier Science
Publication: July 12, 2002
Imprint: Pergamon
Language: English

This volume, number 23 in the "Tetrahedron Organic Chemistry" series, presents organolithium chemistry from the perspective of a synthetic organic chemist, drawing from the synthetic literature to present a unified overview of how organolithiums can be used to make molecules. The development of methods for the regioselective synthesis of organolithiums has replaced their image of indiscriminate high reactivity with one of controllable and subtle selectivity. Organolithium chemistry has a central role in the selective construction of C-C bonds in both simple and complex molecules, and for example has arguably overtaken aromatic electrophilic substitution as the most powerful method for regioselective functionalisation of aromatic rings. The twin themes of reactivity and selectivity run through the book, which reviews the ways by which organolithiums may be formed and the ways in which they react. Topics include advances in directed metallation, reductive lithiation and organolithium cyclisation reactions, along with a discussion of organolithium stereochemistry and the role played by ligands such as (-)-sparteine.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This volume, number 23 in the "Tetrahedron Organic Chemistry" series, presents organolithium chemistry from the perspective of a synthetic organic chemist, drawing from the synthetic literature to present a unified overview of how organolithiums can be used to make molecules. The development of methods for the regioselective synthesis of organolithiums has replaced their image of indiscriminate high reactivity with one of controllable and subtle selectivity. Organolithium chemistry has a central role in the selective construction of C-C bonds in both simple and complex molecules, and for example has arguably overtaken aromatic electrophilic substitution as the most powerful method for regioselective functionalisation of aromatic rings. The twin themes of reactivity and selectivity run through the book, which reviews the ways by which organolithiums may be formed and the ways in which they react. Topics include advances in directed metallation, reductive lithiation and organolithium cyclisation reactions, along with a discussion of organolithium stereochemistry and the role played by ligands such as (-)-sparteine.

More books from Elsevier Science

Cover of the book Progress in Heterocyclic Chemistry by Jonathan Clayden
Cover of the book Frontiers in Computational Chemistry: Volume 2 by Jonathan Clayden
Cover of the book Spatial Capture-Recapture by Jonathan Clayden
Cover of the book Information Literacy and Cultural Heritage by Jonathan Clayden
Cover of the book Solid State Physics by Jonathan Clayden
Cover of the book Principles of Colour and Appearance Measurement by Jonathan Clayden
Cover of the book Fish Immunology by Jonathan Clayden
Cover of the book Recent Advances in Magnetic Insulators - From Spintronics to Microwave Applications by Jonathan Clayden
Cover of the book Micromechanics of Composites by Jonathan Clayden
Cover of the book Assessment of Safety and Risk with a Microscopic Model of Detonation by Jonathan Clayden
Cover of the book Physical Metallurgy by Jonathan Clayden
Cover of the book Laboratory Methods in Enzymology: Protein Part A by Jonathan Clayden
Cover of the book Nanotechnology Methods for Neurological Diseases and Brain Tumors by Jonathan Clayden
Cover of the book Gas-Liquid And Liquid-Liquid Separators by Jonathan Clayden
Cover of the book Designing User Interfaces for an Aging Population by Jonathan Clayden
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy