Outer Membrane Vesicles of Bacteria

Nonfiction, Health & Well Being, Medical, Medical Science, Microbiology, Immunology
Cover of the book Outer Membrane Vesicles of Bacteria by S.N. Chatterjee, Keya Chaudhuri, Springer Berlin Heidelberg
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Author: S.N. Chatterjee, Keya Chaudhuri ISBN: 9783642305269
Publisher: Springer Berlin Heidelberg Publication: August 1, 2012
Imprint: Springer Language: English
Author: S.N. Chatterjee, Keya Chaudhuri
ISBN: 9783642305269
Publisher: Springer Berlin Heidelberg
Publication: August 1, 2012
Imprint: Springer
Language: English

This book provides a detailed account of the physico-chemical properties and biological functions of the outer membrane vesicles (OMVs) of different pathogenic and non-pathogenic Gram-negative bacteria. It also includes an authentic record of the first systematic study that discovered the mechanism of OMV formation by a pathogen, Vibrio cholerae, and proposed that the process represented a novel secretory activity of bacteria. Furthermore, the authors present clinical and laboratory data on the use of OMVs as immunogens, as effective and licensed vaccines against Neisseria meningitidis serogroup B infections and on the development of more effective vaccines against other human and animal pathogens including Vibrio cholerae. This volume thus bears witness to the emerging revolution in the field of vaccines against pathogens and closes with a discussion of open questions and future research on OMVs.

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This book provides a detailed account of the physico-chemical properties and biological functions of the outer membrane vesicles (OMVs) of different pathogenic and non-pathogenic Gram-negative bacteria. It also includes an authentic record of the first systematic study that discovered the mechanism of OMV formation by a pathogen, Vibrio cholerae, and proposed that the process represented a novel secretory activity of bacteria. Furthermore, the authors present clinical and laboratory data on the use of OMVs as immunogens, as effective and licensed vaccines against Neisseria meningitidis serogroup B infections and on the development of more effective vaccines against other human and animal pathogens including Vibrio cholerae. This volume thus bears witness to the emerging revolution in the field of vaccines against pathogens and closes with a discussion of open questions and future research on OMVs.

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