Phosphoinositide 3-kinase in Health and Disease

Volume 1

Nonfiction, Health & Well Being, Medical, Medical Science, Physiology, Specialties, Oncology
Cover of the book Phosphoinositide 3-kinase in Health and Disease by , Springer Berlin Heidelberg
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Author: ISBN: 9783642136634
Publisher: Springer Berlin Heidelberg Publication: October 17, 2010
Imprint: Springer Language: English
Author:
ISBN: 9783642136634
Publisher: Springer Berlin Heidelberg
Publication: October 17, 2010
Imprint: Springer
Language: English

From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here we give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here

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From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here we give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here

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