Polycomb Group Proteins

Nonfiction, Science & Nature, Science, Other Sciences, Molecular Biology, Biological Sciences, Genetics
Cover of the book Polycomb Group Proteins by Vincenzo Pirrotta, Elsevier Science
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Vincenzo Pirrotta ISBN: 9780128098226
Publisher: Elsevier Science Publication: January 1, 2017
Imprint: Academic Press Language: English
Author: Vincenzo Pirrotta
ISBN: 9780128098226
Publisher: Elsevier Science
Publication: January 1, 2017
Imprint: Academic Press
Language: English

Polycomb Group Proteins is a comprehensive volume detailing the mechanisms that are key to the management of genome function in many different contexts, from embryonic stem cells to terminal differentiation. The book discusses the regulation of cell lineages, cell proliferation, apoptosis, X chromosome inactivation, and most major genome programming choices.

In the last few years, the biochemical understanding of PRC1-type complexes has greatly expanded in terms of the number of components involved and the intricacies of their interactions. The functionalities of these various complexes and their components are not all well understood, but recent work has shown an important division of labor and roles in the recruitment of stable binding in the ability to lay the groundwork of histone modifications and in the epigenetic maintenance of repressed states.

In an effort to provide clarity in this topical research area, the book provides a cluster of chapters that deal with variant PRC1 complexes, their taxonomy, their components, their interactions, and what is known of their functions.

  • Provides topical coverage on accessory components that are known to be involved in PcG recruitment in Drosophila and their less understood role in mammals
  • Includes dedicated sections on PRC1 complexes and PRC2 complexes for quick reference
  • Features the role of RNA molecules in different aspects of Polycomb proteins involvement in epigenetic regulation, beginning with the key role of the Xist RNA in recruiting and spreading PcG complexes on the inactive X chromosome
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Polycomb Group Proteins is a comprehensive volume detailing the mechanisms that are key to the management of genome function in many different contexts, from embryonic stem cells to terminal differentiation. The book discusses the regulation of cell lineages, cell proliferation, apoptosis, X chromosome inactivation, and most major genome programming choices.

In the last few years, the biochemical understanding of PRC1-type complexes has greatly expanded in terms of the number of components involved and the intricacies of their interactions. The functionalities of these various complexes and their components are not all well understood, but recent work has shown an important division of labor and roles in the recruitment of stable binding in the ability to lay the groundwork of histone modifications and in the epigenetic maintenance of repressed states.

In an effort to provide clarity in this topical research area, the book provides a cluster of chapters that deal with variant PRC1 complexes, their taxonomy, their components, their interactions, and what is known of their functions.

More books from Elsevier Science

Cover of the book Genetically Modified Plants by Vincenzo Pirrotta
Cover of the book Computer Aided Property Estimation for Process and Product Design by Vincenzo Pirrotta
Cover of the book Petroleum Geology of Libya by Vincenzo Pirrotta
Cover of the book Biology of T Cells - Part B by Vincenzo Pirrotta
Cover of the book Biomarkers and Biosensors by Vincenzo Pirrotta
Cover of the book Information Resources in Toxicology by Vincenzo Pirrotta
Cover of the book Mathematical Achievements of Pre-modern Indian Mathematicians by Vincenzo Pirrotta
Cover of the book Chemical and Biochemical Approaches for the Study of Anesthetic Function, Part A by Vincenzo Pirrotta
Cover of the book Structural Behavior of Asphalt Pavements by Vincenzo Pirrotta
Cover of the book The RF in RFID by Vincenzo Pirrotta
Cover of the book Statistical Mechanics by Vincenzo Pirrotta
Cover of the book The Cardiovascular System by Vincenzo Pirrotta
Cover of the book Advances in Agronomy by Vincenzo Pirrotta
Cover of the book International Review of Cell and Molecular Biology by Vincenzo Pirrotta
Cover of the book Smart Cities and Homes by Vincenzo Pirrotta
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy