Progestins and the Mammary Gland

From Basic Science to Clinical Applications

Nonfiction, Health & Well Being, Health, Ailments & Diseases, Genetic, Science & Nature, Science, Biological Sciences, Zoology
Cover of the book Progestins and the Mammary Gland by , Springer Berlin Heidelberg
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Author: ISBN: 9783540734932
Publisher: Springer Berlin Heidelberg Publication: March 27, 2008
Imprint: Springer Language: English
Author:
ISBN: 9783540734932
Publisher: Springer Berlin Heidelberg
Publication: March 27, 2008
Imprint: Springer
Language: English

Progestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21–23 March 2007. Genetic mouse models helped to elucidate the role of progestins, both in normal breast development and in disease. Mechanistic molecular studies inspired the design of new progestins with improved tissue selectivity. In addition, the clinical impact of progesterone receptor agonists and antagonists for the prevention and treatment of breast cancer was discussed.

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Progestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21–23 March 2007. Genetic mouse models helped to elucidate the role of progestins, both in normal breast development and in disease. Mechanistic molecular studies inspired the design of new progestins with improved tissue selectivity. In addition, the clinical impact of progesterone receptor agonists and antagonists for the prevention and treatment of breast cancer was discussed.

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