Regulation of Cell Proliferation and Differentiation

Nonfiction, Health & Well Being, Medical, Medical Science, Anatomy
Cover of the book Regulation of Cell Proliferation and Differentiation by , Springer US
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781461588467
Publisher: Springer US Publication: December 6, 2012
Imprint: Springer Language: English
Author:
ISBN: 9781461588467
Publisher: Springer US
Publication: December 6, 2012
Imprint: Springer
Language: English

In 1974 The National Institute on Aging established a somatic cell genetic resource for aging research at the Institute for Medical Research in Camden, New Jersey. Within this program there is a yearly workshop to promote theory and concept develop­ ment in aging research with the specific purpose of addressing the use of genetically marked cells for aging research and to stimulate interest in aging research by workers in a variety of disciplines. This monograph, The Regulation of Cell Proliferation and Differentiation, is the result of the first workshop held May 15-17, 1975. The concept of the workshop was to consider two main areas: First, a discussion of clinical syndromes expressing as a major manifestation excessive growth, deficient growth or failure to thrive; and second, to present work in cellular and molecular biology on a model system suitable for in vitro study of regulation of cell proliferation and diff2rentiation. The model selected for this was skeletal muscle. It has been widely accepted that normal somatic cells from individual human donors display limited replicative lifespans when cultivated in vitro (1,2). That such "clonal senescence" may be related to in vivo aging is suggested by observations relating the replicative lifespans of cultures to donor age (3-5,13) donor genotype (4-7) and donor's tissue of origin (5,8). A variety of theories have been developed to explain in vitro clonal senescence (9).

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

In 1974 The National Institute on Aging established a somatic cell genetic resource for aging research at the Institute for Medical Research in Camden, New Jersey. Within this program there is a yearly workshop to promote theory and concept develop­ ment in aging research with the specific purpose of addressing the use of genetically marked cells for aging research and to stimulate interest in aging research by workers in a variety of disciplines. This monograph, The Regulation of Cell Proliferation and Differentiation, is the result of the first workshop held May 15-17, 1975. The concept of the workshop was to consider two main areas: First, a discussion of clinical syndromes expressing as a major manifestation excessive growth, deficient growth or failure to thrive; and second, to present work in cellular and molecular biology on a model system suitable for in vitro study of regulation of cell proliferation and diff2rentiation. The model selected for this was skeletal muscle. It has been widely accepted that normal somatic cells from individual human donors display limited replicative lifespans when cultivated in vitro (1,2). That such "clonal senescence" may be related to in vivo aging is suggested by observations relating the replicative lifespans of cultures to donor age (3-5,13) donor genotype (4-7) and donor's tissue of origin (5,8). A variety of theories have been developed to explain in vitro clonal senescence (9).

More books from Springer US

Cover of the book The Impact of Space Science on Mankind by
Cover of the book Molecular Biology of Acute Lung Injury by
Cover of the book Static and Dynamic Performance Limitations for High Speed D/A Converters by
Cover of the book Health Psychology by
Cover of the book Learning, Speech, and the Complex Effects of Punishment by
Cover of the book Handbook of EOQ Inventory Problems by
Cover of the book Doctors’ Marriages by
Cover of the book Responding to the Homeless by
Cover of the book Microarray Detection and Characterization of Bacterial Foodborne Pathogens by
Cover of the book Relational Frame Theory by
Cover of the book Social Referencing and the Social Construction of Reality in Infancy by
Cover of the book The Physiology of Psychological Disorders by
Cover of the book Juvenile Psychiatry and the Law by
Cover of the book Inventory Management by
Cover of the book Challenges of Psychoanalysis in the 21st Century by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy