Selective Estrogen Receptor Modulators

Research and Clinical Applications

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Endocrinology & Metabolism
Cover of the book Selective Estrogen Receptor Modulators by , Humana Press
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781592591572
Publisher: Humana Press Publication: January 18, 2002
Imprint: Humana Language: English
Author:
ISBN: 9781592591572
Publisher: Humana Press
Publication: January 18, 2002
Imprint: Humana
Language: English

Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their effects on the reproductive, vascular, skeletal, and central nervous systems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their effects on the reproductive, vascular, skeletal, and central nervous systems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.

More books from Humana Press

Cover of the book Microwave Techniques and Protocols by
Cover of the book Nuclear Cardiology: The Basics by
Cover of the book Clinical Pathology of Pancreatic Disorders by
Cover of the book Chemical and Physical Signatures for Microbial Forensics by
Cover of the book Drug Delivery Systems in Cancer Therapy by
Cover of the book Handbook of Cerebrovascular Disease and Neurointerventional Technique by
Cover of the book Buprenorphine Therapy of Opiate Addiction by
Cover of the book Liquid Chromatography in Clinical Analysis by
Cover of the book Pediatric Hypertension by
Cover of the book Current Controversies in Bone Marrow Transplantation by
Cover of the book The Nature and Prospect of Bioethics by
Cover of the book Hematopoietic Stem Cell Transplantation by
Cover of the book Inflammatory Bowel Disease by
Cover of the book Diagnostic, Prognostic and Therapeutic Value of Gene Signatures by
Cover of the book Comprehensive Cardiovascular Medicine in the Primary Care Setting by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy