Stimulation of Trigeminal Afferents Improves Motor Recovery After Facial Nerve Injury

Functional, Electrophysiological and Morphological Proofs

Nonfiction, Health & Well Being, Medical, Surgery, Neurosurgery, Specialties, Internal Medicine, Neuroscience, Science & Nature, Science
Cover of the book Stimulation of Trigeminal Afferents Improves Motor Recovery After Facial Nerve Injury by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov, Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov ISBN: 9783642333118
Publisher: Springer Berlin Heidelberg Publication: December 15, 2012
Imprint: Springer Language: English
Author: Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
ISBN: 9783642333118
Publisher: Springer Berlin Heidelberg
Publication: December 15, 2012
Imprint: Springer
Language: English

Recovery of mimic function after facial nerve transection is poor: the successful regrowth of axotomized motoneurons to their targets is compromised by (i) poor axonal navigation and excessive collateral branching, (ii) abnormal exchange of nerve impulses between adjacent regrowing axons and (iii) insufficient synaptic input to facial motoneurons. As a result, axotomized motoneurons get hyperexcitable and unable to discharge. Since improvement of growth cone navigation and reduction of the ephaptic cross-talk between axons turn out be very difficult, the authorsa concentrated on the third detrimental component and proposed that an intensification of the trigeminal input to axotomized electrophysiologically silent facial motoneurons might improve specificity of reinnervation. To test the hypothesis they compared behavioral, electrophysiological and morphological parameters after single reconstructive surgery on the facial nerve with those obtained after identical facial nerve surgery, but combined with direct or indirect stimulation of the ipsilateral infraorbital (ION) nerve.  The authors found that in all cases trigeminal stimulation was beneficial for the outcome by improving the quality of target reinnervation and recovery of vibrissal motor performance.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Recovery of mimic function after facial nerve transection is poor: the successful regrowth of axotomized motoneurons to their targets is compromised by (i) poor axonal navigation and excessive collateral branching, (ii) abnormal exchange of nerve impulses between adjacent regrowing axons and (iii) insufficient synaptic input to facial motoneurons. As a result, axotomized motoneurons get hyperexcitable and unable to discharge. Since improvement of growth cone navigation and reduction of the ephaptic cross-talk between axons turn out be very difficult, the authorsa concentrated on the third detrimental component and proposed that an intensification of the trigeminal input to axotomized electrophysiologically silent facial motoneurons might improve specificity of reinnervation. To test the hypothesis they compared behavioral, electrophysiological and morphological parameters after single reconstructive surgery on the facial nerve with those obtained after identical facial nerve surgery, but combined with direct or indirect stimulation of the ipsilateral infraorbital (ION) nerve.  The authors found that in all cases trigeminal stimulation was beneficial for the outcome by improving the quality of target reinnervation and recovery of vibrissal motor performance.

More books from Springer Berlin Heidelberg

Cover of the book Nucleic Acid Polymerases by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book Digitale Führung by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book The Economics of Natural Gas Storage by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book Learning C# by Programming Games by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book Transactions on Computational Science XXIV by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book Epigenetic Regulation of Lymphocyte Development by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book Magic of Minerals and Rocks by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book Skeletterkrankungen by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book Handbuch Entwicklungs- und Erziehungspsychologie by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book Protection of Traditional Cultural Expressions in Latin America by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book Centrifugal Pumps by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book Atlas of Antarctica by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book Proceedings of China Modern Logistics Engineering by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book Comparative Effectiveness and Efficacy Research and Analysis for Practice (CEERAP) by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
Cover of the book The Natural Environment and the Biogeochemical Cycles by Emmanouil Skouras, Stoyan Pavlov, Habib Bendella, Doychin N. Angelov
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy