Studies on Renal Disorders

Nonfiction, Science & Nature, Science, Biological Sciences, Cytology, Other Sciences, Molecular Biology
Cover of the book Studies on Renal Disorders by , Humana Press
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781607618577
Publisher: Humana Press Publication: December 17, 2010
Imprint: Humana Language: English
Author:
ISBN: 9781607618577
Publisher: Humana Press
Publication: December 17, 2010
Imprint: Humana
Language: English

Conditions such as oxidative stress and hypoxia, which have a generalized impact on the oxygen metabolism, have been implicated in the genesis of kidney disease. This means that deepening our understanding of the pathobiology of oxygen metabolism in such diseases could be a fruitful path towards tangible clinical benefits. Studies in Renal Disorder collects reviews from leading researchers and clinical scientists working in exactly this field, providing an overview of the latest advances. The causal role of impaired oxygen metabolism in kidney disease has numerous clinical implications. It affects our understanding of the therapeutic benefits accruing from anti-hypertensive agents; the way we control hyperglycemia/hyperinsulinemia and hyperlipidemia; and our use of dietary approaches to the correction of obesity. The defensive mechanisms against oxidative stress, such as the Nrf2-Keap1 system, and hypoxia, such as the PHD-HIF system, have recently been explored in various cells, including kidney cells. These mechanisms include intracellular sensors for oxidative stress and hypoxia. This means that novel approaches targeting these sensors may offer clinical benefits in kidney disease in which oxidative stress and/or hypoxia is a final, common pathway.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Conditions such as oxidative stress and hypoxia, which have a generalized impact on the oxygen metabolism, have been implicated in the genesis of kidney disease. This means that deepening our understanding of the pathobiology of oxygen metabolism in such diseases could be a fruitful path towards tangible clinical benefits. Studies in Renal Disorder collects reviews from leading researchers and clinical scientists working in exactly this field, providing an overview of the latest advances. The causal role of impaired oxygen metabolism in kidney disease has numerous clinical implications. It affects our understanding of the therapeutic benefits accruing from anti-hypertensive agents; the way we control hyperglycemia/hyperinsulinemia and hyperlipidemia; and our use of dietary approaches to the correction of obesity. The defensive mechanisms against oxidative stress, such as the Nrf2-Keap1 system, and hypoxia, such as the PHD-HIF system, have recently been explored in various cells, including kidney cells. These mechanisms include intracellular sensors for oxidative stress and hypoxia. This means that novel approaches targeting these sensors may offer clinical benefits in kidney disease in which oxidative stress and/or hypoxia is a final, common pathway.

More books from Humana Press

Cover of the book Platinum-Based Drugs in Cancer Therapy by
Cover of the book Molecular and Translational Vascular Medicine by
Cover of the book Adipose Tissue and Adipokines in Health and Disease by
Cover of the book EGFR Signaling Networks in Cancer Therapy by
Cover of the book Endoscopic Therapy for Barrett's Esophagus by
Cover of the book Studies on Veterinary Medicine by
Cover of the book Pediatric Urology by
Cover of the book IGF and Nutrition in Health and Disease by
Cover of the book Fibrocystic Diseases of the Liver by
Cover of the book Parkinson's Disease and Nonmotor Dysfunction by
Cover of the book Omega-6/3 Fatty Acids by
Cover of the book Preventive Nutrition by
Cover of the book Clinical Handbook of Insomnia by
Cover of the book Oxidative Neural Injury by
Cover of the book Chemoradiation in Cancer Therapy by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy