Synthetic Biology

From iGEM to the Artificial Cell

Nonfiction, Science & Nature, Science, Biological Sciences, Microbiology, Genetics, Health & Well Being, Medical
Cover of the book Synthetic Biology by Manuel Porcar, Juli Peretó, Springer Netherlands
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Author: Manuel Porcar, Juli Peretó ISBN: 9789401793827
Publisher: Springer Netherlands Publication: September 9, 2014
Imprint: Springer Language: English
Author: Manuel Porcar, Juli Peretó
ISBN: 9789401793827
Publisher: Springer Netherlands
Publication: September 9, 2014
Imprint: Springer
Language: English

Synthetic Biology (SB) is a revolutionary discipline with a vast range of practical applications, but is SB research really based on engineering principles? Does it contributing to the artificial synthesis of life or does it utilise approaches sufficiently advanced to fall outside the scope of biotechnology or metabolic engineering? This volume reviews the development of SB and includes the major milestones of the discipline, the ‘top-down’ and ‘bottom-up’ approaches towards the construction of an artificial cell and the development of the “iGEM” competition. We conclude that SB is an emerging field with extraordinary technological potential, but that most research projects actually are an extension of metabolic engineering since the complexity of living organisms, their tight dependence on evolution and our limited knowledge of the interactions between the molecules, actually make life difficult to engineer.

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Synthetic Biology (SB) is a revolutionary discipline with a vast range of practical applications, but is SB research really based on engineering principles? Does it contributing to the artificial synthesis of life or does it utilise approaches sufficiently advanced to fall outside the scope of biotechnology or metabolic engineering? This volume reviews the development of SB and includes the major milestones of the discipline, the ‘top-down’ and ‘bottom-up’ approaches towards the construction of an artificial cell and the development of the “iGEM” competition. We conclude that SB is an emerging field with extraordinary technological potential, but that most research projects actually are an extension of metabolic engineering since the complexity of living organisms, their tight dependence on evolution and our limited knowledge of the interactions between the molecules, actually make life difficult to engineer.

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