Techniques for the Analysis of Membrane Proteins

Kids, Natural World, Nonfiction, Reference & Language, Education & Teaching, Science & Nature, Science
Cover of the book Techniques for the Analysis of Membrane Proteins by , Springer Netherlands
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9789400940857
Publisher: Springer Netherlands Publication: December 6, 2012
Imprint: Springer Language: English
Author:
ISBN: 9789400940857
Publisher: Springer Netherlands
Publication: December 6, 2012
Imprint: Springer
Language: English

A preface should justify the existence of the book it precedes and this is invariably done in scientific texts by reference to the explosive growth of the field since the last such volume appeared. In molecular biology, most fields can be justifiably described as growing explosively, as should be the case for a young and vigorous science, but the study of membrane proteins stands out as one which has taken giant strides in the last few years. Ignorance of the structure and function of membrane proteins at the molecular level was certainly not due to lack of interest but rather was a result of lack of appropriate techniques. It has above all been the development of new experimental methods which has wrenched membrane biochemistry out of what Anthony Martonosi fetchingly called its 'romantic phase' (Le. lots of ideas and few facts), into an era when the determination of membrane protein structure and mechanism is a reasonable goal. Membrane proteins are generally classified as peripheral or integral. Peripheral proteins are relatively easily dissociated from membranes by mild treatments whence their study is essentially no different to that of soluble proteins. This book therefore concentrates on integral proteins which are strongly bound to the membrane by hydrophobic interactions with lipids. A crucial step in their study is of necessity the d~velopment of methods of solubilization and purification under non-denaturing conditions.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

A preface should justify the existence of the book it precedes and this is invariably done in scientific texts by reference to the explosive growth of the field since the last such volume appeared. In molecular biology, most fields can be justifiably described as growing explosively, as should be the case for a young and vigorous science, but the study of membrane proteins stands out as one which has taken giant strides in the last few years. Ignorance of the structure and function of membrane proteins at the molecular level was certainly not due to lack of interest but rather was a result of lack of appropriate techniques. It has above all been the development of new experimental methods which has wrenched membrane biochemistry out of what Anthony Martonosi fetchingly called its 'romantic phase' (Le. lots of ideas and few facts), into an era when the determination of membrane protein structure and mechanism is a reasonable goal. Membrane proteins are generally classified as peripheral or integral. Peripheral proteins are relatively easily dissociated from membranes by mild treatments whence their study is essentially no different to that of soluble proteins. This book therefore concentrates on integral proteins which are strongly bound to the membrane by hydrophobic interactions with lipids. A crucial step in their study is of necessity the d~velopment of methods of solubilization and purification under non-denaturing conditions.

More books from Springer Netherlands

Cover of the book Anaphora in Celtic and Universal Grammar by
Cover of the book Transforming Enterprise Cloud Services by
Cover of the book Fission-Track Dating by
Cover of the book Increasing Psychological Well-being in Clinical and Educational Settings by
Cover of the book The Ocean Carbon Cycle and Climate by
Cover of the book ECODESIGN -- The Competitive Advantage by
Cover of the book The Paleobiology of Australopithecus by
Cover of the book The Chloroplast by
Cover of the book Qanat Knowledge by
Cover of the book Critical Voices in Teacher Education by
Cover of the book Integrated Pest Management by
Cover of the book Knowing from Words by
Cover of the book Collected Papers on Epistemology, Philosophy of Science and History of Philosophy by
Cover of the book Climate Change: Significance for Agriculture and Forestry by
Cover of the book Photosensitizers in Medicine, Environment, and Security by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy