Temporal Aspects of Therapeutics

Kids, Natural World, Nonfiction, Reference & Language, Education & Teaching, Science & Nature, Science
Cover of the book Temporal Aspects of Therapeutics by , Springer US
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781468428476
Publisher: Springer US Publication: December 6, 2012
Imprint: Springer Language: English
Author:
ISBN: 9781468428476
Publisher: Springer US
Publication: December 6, 2012
Imprint: Springer
Language: English

Drugs are molecular agents of a physician's purpose. Discussions of their mechanisms of action center upon biochemical processes, even though the therapeutic intent may be to create an effect at a higher level of organization. We often prescribe to stop pain, increase vigor, assure sleep, curtail infection, alleviate inflammation, elevate mood, etc. To achieve rational therapy at high levels of organization it is not enough to know the molecular structures of drugs, and the points at which they couple into biochemical reaction chains. Such knowledge deals with static concepts, whereas the biosystems we treat extend in the dimensions of time as well as in those of space. Even when "resting", a biosystem manifests a dynamic stability, and sustains numerous processes whose successive states follow trajectories in time. A chemical message is not necessarily received by a biosystem as the same signal at one time as at another. Studies of cell cycle biochemistry, and of circadian variations in toxicity of some agents, have emphasized the importance of time as an aspect of therapeutics. In this volume, temporal aspects of living systems are considered. In the first section they are dealt with from the point of view of general design principles, in three papers by Morowitz, by Yates and Iberall, and by Winfree. In the second section, papers by Kaiser and by Thompson present accounts of sequential events in fundamental subcellular processes.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Drugs are molecular agents of a physician's purpose. Discussions of their mechanisms of action center upon biochemical processes, even though the therapeutic intent may be to create an effect at a higher level of organization. We often prescribe to stop pain, increase vigor, assure sleep, curtail infection, alleviate inflammation, elevate mood, etc. To achieve rational therapy at high levels of organization it is not enough to know the molecular structures of drugs, and the points at which they couple into biochemical reaction chains. Such knowledge deals with static concepts, whereas the biosystems we treat extend in the dimensions of time as well as in those of space. Even when "resting", a biosystem manifests a dynamic stability, and sustains numerous processes whose successive states follow trajectories in time. A chemical message is not necessarily received by a biosystem as the same signal at one time as at another. Studies of cell cycle biochemistry, and of circadian variations in toxicity of some agents, have emphasized the importance of time as an aspect of therapeutics. In this volume, temporal aspects of living systems are considered. In the first section they are dealt with from the point of view of general design principles, in three papers by Morowitz, by Yates and Iberall, and by Winfree. In the second section, papers by Kaiser and by Thompson present accounts of sequential events in fundamental subcellular processes.

More books from Springer US

Cover of the book Population and Family in the Low Countries by
Cover of the book Building Engineering and Systems Design by
Cover of the book Information, Organization and Information Systems Design by
Cover of the book Organizational Semiotics by
Cover of the book The Mathematical Gardner by
Cover of the book Diabetes in Elderly People by
Cover of the book Endocrine Therapies in Breast and Prostate Cancer by
Cover of the book Learning to Serve by
Cover of the book Criminal Court Consultation by
Cover of the book Contemporary American Jewelry Design by
Cover of the book Cellular Signals Controlling Uterine Function by
Cover of the book Communication Problems in Autism by
Cover of the book Manual of Pathology of the Human Placenta by
Cover of the book Radiation Science for Physicians and Public Health Workers by
Cover of the book New Directions in Real Estate Finance and Investment by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy