The Cornea in Normal Condition and in Groenouw’s Macular Dystrophy

Nonfiction, Health & Well Being, Medical, Specialties, Ophthalmology
Cover of the book The Cornea in Normal Condition and in Groenouw’s Macular Dystrophy by , Springer Netherlands
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9789400991774
Publisher: Springer Netherlands Publication: December 6, 2012
Imprint: Springer Language: English
Author:
ISBN: 9789400991774
Publisher: Springer Netherlands
Publication: December 6, 2012
Imprint: Springer
Language: English

The three most striking characteristics of the cornea are: a) Its structure or rather its perfectly regular architectonic, by virtue of which it is transparent. b) The absence of vessels, the cornea being nourished by the perilimbic vessels, the endothelial surface in communication with the aqueous humour and the epithelial surface in contact with the pre-corneal film. c) The very slow turnover of the cells, that is to say the keratocytes, with the result that the metabolism of the cornea is very weak. It is this third characteristic which justifies our present investigation. The keratocytes, which are apparently inactive, have in fact a latent activity. They can be activated by central corneal incisions and also by tissue cultures. Under either of those conditions, the keratocytes become very active, develop all the cytoplasmic organites and produce mucopoly­ saccharides as well as the precursors of the collagen (Fig. 1). In order to study the pathological keratocyte, we chose a storage disease, wherein the catabolism of the mucopolysaccharides is blocked, namely the macular dystrophy of the cornea. We undertook the same investigation both for normal and for pathologi­ cal corneas and studied the keratocyte 'in situ' and in tissue cultures using various microscopical and histochemical techniques. In macular dystrophy, we investigated also the deteriorations secondary to the changes in the keratocytes.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

The three most striking characteristics of the cornea are: a) Its structure or rather its perfectly regular architectonic, by virtue of which it is transparent. b) The absence of vessels, the cornea being nourished by the perilimbic vessels, the endothelial surface in communication with the aqueous humour and the epithelial surface in contact with the pre-corneal film. c) The very slow turnover of the cells, that is to say the keratocytes, with the result that the metabolism of the cornea is very weak. It is this third characteristic which justifies our present investigation. The keratocytes, which are apparently inactive, have in fact a latent activity. They can be activated by central corneal incisions and also by tissue cultures. Under either of those conditions, the keratocytes become very active, develop all the cytoplasmic organites and produce mucopoly­ saccharides as well as the precursors of the collagen (Fig. 1). In order to study the pathological keratocyte, we chose a storage disease, wherein the catabolism of the mucopolysaccharides is blocked, namely the macular dystrophy of the cornea. We undertook the same investigation both for normal and for pathologi­ cal corneas and studied the keratocyte 'in situ' and in tissue cultures using various microscopical and histochemical techniques. In macular dystrophy, we investigated also the deteriorations secondary to the changes in the keratocytes.

More books from Springer Netherlands

Cover of the book Guyana: Race and Politics among Africans and East Indians by
Cover of the book Managing Environmental Risk Through Insurance by
Cover of the book Euclid's Heritage. Is Space Three-Dimensional? by
Cover of the book Atlas of Serous Fluid Cytopathology by
Cover of the book Population Genetics by
Cover of the book Intonation by
Cover of the book The Danube Swabians by
Cover of the book Improving Disaster Resilience and Mitigation - IT Means and Tools by
Cover of the book The Effects of Standardized Testing by
Cover of the book Atlas of Parasitic Pathology by
Cover of the book MicroRNA Cancer Regulation by
Cover of the book Science Studies as Naturalized Philosophy by
Cover of the book Medicine and Society, New Perspectives in Continental Philosophy by
Cover of the book Justice and Health Care by
Cover of the book Nanotechnological Basis for Advanced Sensors by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy