The Lock and Key of Medicine

Monoclonal Antibodies and the Transformation of Healthcare

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology, Reference, History, Science & Nature, Science, Other Sciences
Cover of the book The Lock and Key of Medicine by Lara V. Marks, Yale University Press
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Lara V. Marks ISBN: 9780300213522
Publisher: Yale University Press Publication: June 28, 2015
Imprint: Yale University Press Language: English
Author: Lara V. Marks
ISBN: 9780300213522
Publisher: Yale University Press
Publication: June 28, 2015
Imprint: Yale University Press
Language: English
This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies. Often referred to as Mabs, they are unfamiliar to most nonscientists, yet these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. Discovered in the mid-1970s in the laboratory where Watson and Crick had earlier unveiled the structure of DNA, Mabs have radically changed understandings of the pathways of disease. They have enabled faster, cheaper, and more accurate clinical diagnostic testing on a vast scale. And they have played a fundamental role in pharmaceutical innovation, leading to such developments as recombinant interferon and insulin, and personalized drug therapies such as Herceptin. Today Mabs constitute six of the world’s top ten blockbuster drugs and make up a third of new introduced treatments.
 
Lara V. Marks recounts the risks and opposition that a daring handful of individuals faced while discovering and developing Mabs, and she addresses the related scientific, medical, technological, business, and social challenges that arose. She offers a saga of entrepreneurs whose persistence and creativity ultimately changed the healthcare landscape and brought untold relief to millions of patients. Even so, as Marks shows, controversies over Mabs remain, and she examines current debates over the costs and effectiveness of these innovative drugs.
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies. Often referred to as Mabs, they are unfamiliar to most nonscientists, yet these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. Discovered in the mid-1970s in the laboratory where Watson and Crick had earlier unveiled the structure of DNA, Mabs have radically changed understandings of the pathways of disease. They have enabled faster, cheaper, and more accurate clinical diagnostic testing on a vast scale. And they have played a fundamental role in pharmaceutical innovation, leading to such developments as recombinant interferon and insulin, and personalized drug therapies such as Herceptin. Today Mabs constitute six of the world’s top ten blockbuster drugs and make up a third of new introduced treatments.
 
Lara V. Marks recounts the risks and opposition that a daring handful of individuals faced while discovering and developing Mabs, and she addresses the related scientific, medical, technological, business, and social challenges that arose. She offers a saga of entrepreneurs whose persistence and creativity ultimately changed the healthcare landscape and brought untold relief to millions of patients. Even so, as Marks shows, controversies over Mabs remain, and she examines current debates over the costs and effectiveness of these innovative drugs.

More books from Yale University Press

Cover of the book America?s Inadvertent Empire by Lara V. Marks
Cover of the book The Winchester by Lara V. Marks
Cover of the book Nature by Design by Lara V. Marks
Cover of the book The Strike That Changed New York by Lara V. Marks
Cover of the book Italian Venice by Lara V. Marks
Cover of the book One World: The Ethics of Globalization by Lara V. Marks
Cover of the book Virtual Justice: The New Laws of Online Worlds by Lara V. Marks
Cover of the book Abraham's Children: Liberty and Tolerance in an Age of Religious Conflict by Lara V. Marks
Cover of the book Russia's Crony Capitalism by Lara V. Marks
Cover of the book Leviathan: Or The Matter, Forme, & Power of a Common-Wealth Ecclesiasticall and Civill by Lara V. Marks
Cover of the book Interpreting Communicative Language Teaching by Lara V. Marks
Cover of the book Nights Out: Life in Cosmopolitan London by Lara V. Marks
Cover of the book Solomon's Secret Arts by Lara V. Marks
Cover of the book The Selected Correspondence of Aaron Copland by Lara V. Marks
Cover of the book Dispatches from Planet 3 by Lara V. Marks
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy