The Networking of Chaperones by Co-chaperones

Control of Cellular Protein Homeostasis

Nonfiction, Science & Nature, Science, Biological Sciences, Biochemistry, Health & Well Being, Medical
Cover of the book The Networking of Chaperones by Co-chaperones by , Springer International Publishing
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Author: ISBN: 9783319117317
Publisher: Springer International Publishing Publication: December 8, 2014
Imprint: Springer Language: English
Author:
ISBN: 9783319117317
Publisher: Springer International Publishing
Publication: December 8, 2014
Imprint: Springer
Language: English

Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.

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Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.

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