The New Paradigm of Immunity to Tuberculosis

Nonfiction, Health & Well Being, Medical, Medical Science, Microbiology, Immunology
Cover of the book The New Paradigm of Immunity to Tuberculosis by , Springer New York
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Author: ISBN: 9781461461111
Publisher: Springer New York Publication: March 12, 2013
Imprint: Springer Language: English
Author:
ISBN: 9781461461111
Publisher: Springer New York
Publication: March 12, 2013
Imprint: Springer
Language: English

This book illustrates the intimate relationship between alveolar macrophages and Mycobacterium tuberculosis (M.tb.), and the former’s role in both innate and adaptive immunity against M.tb. It covers research done over the last decade. It also explores the role of macrophage death following infection with M.tb. in determining whether successful immunity is stimulated, or whether clinical disease develops; furthermore, the function of host lipid mediators in macrophage death modality are addressed.

The book also illustrates how the balance between prostaglandins and lipoxins determines whether infected macrophages undergo apoptosis or necrosis, which is the ultimate factor in the outcome of infection.

Finally, it is a synthesis of the authors’ recent studies and the studies of others to offer a new understanding of immunity to tuberculosis.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This book illustrates the intimate relationship between alveolar macrophages and Mycobacterium tuberculosis (M.tb.), and the former’s role in both innate and adaptive immunity against M.tb. It covers research done over the last decade. It also explores the role of macrophage death following infection with M.tb. in determining whether successful immunity is stimulated, or whether clinical disease develops; furthermore, the function of host lipid mediators in macrophage death modality are addressed.

The book also illustrates how the balance between prostaglandins and lipoxins determines whether infected macrophages undergo apoptosis or necrosis, which is the ultimate factor in the outcome of infection.

Finally, it is a synthesis of the authors’ recent studies and the studies of others to offer a new understanding of immunity to tuberculosis.

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