The Pathogenic Spirochetes: strategies for evasion of host immunity and persistence

Nonfiction, Health & Well Being, Medical, Medical Science, Microbiology, Immunology
Cover of the book The Pathogenic Spirochetes: strategies for evasion of host immunity and persistence by , Springer US
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Author: ISBN: 9781461454045
Publisher: Springer US Publication: December 9, 2012
Imprint: Springer Language: English
Author:
ISBN: 9781461454045
Publisher: Springer US
Publication: December 9, 2012
Imprint: Springer
Language: English

​This book explores the many mechanisms by which the most prevalent Spirochetal pathogens persist in a healthy immune-competent host.  Among them are the direct and indirect suppression of host immune signals, phase and antigenic variation, escaping recognition by host complement proteins, and seclusion into immune privileged sites.  We also explore antibiotic therapy for control of infection, a baffling topic that lends itself to exalted interpretation.

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​This book explores the many mechanisms by which the most prevalent Spirochetal pathogens persist in a healthy immune-competent host.  Among them are the direct and indirect suppression of host immune signals, phase and antigenic variation, escaping recognition by host complement proteins, and seclusion into immune privileged sites.  We also explore antibiotic therapy for control of infection, a baffling topic that lends itself to exalted interpretation.

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