Thresholds of Genotoxic Carcinogens

From Mechanisms to Regulation

Nonfiction, Health & Well Being, Medical, Specialties, Toxicology, Science & Nature, Science
Cover of the book Thresholds of Genotoxic Carcinogens by , Elsevier Science
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9780128018033
Publisher: Elsevier Science Publication: May 20, 2016
Imprint: Academic Press Language: English
Author:
ISBN: 9780128018033
Publisher: Elsevier Science
Publication: May 20, 2016
Imprint: Academic Press
Language: English

Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation brings together current opinion and research activities from Japan, the US, and Europe on the subject of genotoxic thresholds. In regulation, it is an adage that genotoxic carcinogens have no thresholds for action, and that they impose cancer risk on humans even at very low levels. This policy is frequently called into question as humans possess a number of defense mechanisms including detoxication, DNA repair, and apoptosis, meaning there is a threshold at which these genotoxic carcinogens take action.

The book examines these potential thresholds, describing the potential cancer risks of daily low-level exposure, the mechanisms involved (such as DNA repair, detoxication, translesion DNA synthesis), chemical and statistical methods of analysis, and the ways in which these may be utilized to inform policy. Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation is an essential reference for any professional researchers in genetic toxicology and those involved in toxicological regulation.

  • Unites an international team of experts to provide a balanced overview of the current opinion on thresholds of genotoxic carcinogens
  • Provides all the information readers need to determine a safe threshold for potential genotoxic carcinogens
  • Includes information on the mechanisms of genotoxic carcinogens and how these can inform regulation
  • Serves as an essential reference for any professional researchers in genetic toxicology and those involved in toxicological regulation
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation brings together current opinion and research activities from Japan, the US, and Europe on the subject of genotoxic thresholds. In regulation, it is an adage that genotoxic carcinogens have no thresholds for action, and that they impose cancer risk on humans even at very low levels. This policy is frequently called into question as humans possess a number of defense mechanisms including detoxication, DNA repair, and apoptosis, meaning there is a threshold at which these genotoxic carcinogens take action.

The book examines these potential thresholds, describing the potential cancer risks of daily low-level exposure, the mechanisms involved (such as DNA repair, detoxication, translesion DNA synthesis), chemical and statistical methods of analysis, and the ways in which these may be utilized to inform policy. Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation is an essential reference for any professional researchers in genetic toxicology and those involved in toxicological regulation.

More books from Elsevier Science

Cover of the book Structural Chemistry of Glasses by
Cover of the book The Biology of Cholesterol and Related Steroids by
Cover of the book Brittle Matrix Composites 9 by
Cover of the book Handbook of the Economics of Education by
Cover of the book Essential Chemistry for Formulators of Semisolid and Liquid Dosages by
Cover of the book Pericyclic Reactions by
Cover of the book Functional Glycomics by
Cover of the book Gene Therapy for Viral Infections by
Cover of the book Artificial Vision by
Cover of the book Pyridines: From Lab to Production by
Cover of the book A Guide to Filtration with String Wound Cartridges by
Cover of the book Separation of Isotopes of Biogenic Elements in Two-phase Systems by
Cover of the book Hemophilia and Von Willebrand Disease by
Cover of the book Databook of Biocides by
Cover of the book Computational Nuclear Engineering and Radiological Science Using Python by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy