Vesicle Trafficking in Cancer

Nonfiction, Science & Nature, Science, Other Sciences, Molecular Biology, Health & Well Being, Medical, Specialties, Oncology
Cover of the book Vesicle Trafficking in Cancer by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781461465287
Publisher: Springer New York Publication: April 2, 2013
Imprint: Springer Language: English
Author:
ISBN: 9781461465287
Publisher: Springer New York
Publication: April 2, 2013
Imprint: Springer
Language: English

Endocytosis and vesicular trafficking determine the landscape of the cell’s exterior, namely the density of surface molecules, such as receptors for growth factors and cytokines, adhesion molecules like integrins and cadherins, and a plethora of nutrient carriers. Hence, endocytosis is involved in signal transduction, cell adhesion and migration, as well as metabolism. To exploit these fundamental processes, malignancies subtly and multiply manipulate the endocytosis and the subsequent trafficking of protein cargoes. This is achieved by simultaneously altering the cytoskeleton, vesicle budding, cargo sorting and intracellular degradation. By highlighting the underlying molecular processes and concentrating on specific examples, this book reviews the recent emergence of derailed endocytosis and vesicular trafficking as a landmark of cancer. In-depth understanding of this common feature of tumors might lead the way to drug-induced strategies, able to rectify intracellular trafficking in cancer.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Endocytosis and vesicular trafficking determine the landscape of the cell’s exterior, namely the density of surface molecules, such as receptors for growth factors and cytokines, adhesion molecules like integrins and cadherins, and a plethora of nutrient carriers. Hence, endocytosis is involved in signal transduction, cell adhesion and migration, as well as metabolism. To exploit these fundamental processes, malignancies subtly and multiply manipulate the endocytosis and the subsequent trafficking of protein cargoes. This is achieved by simultaneously altering the cytoskeleton, vesicle budding, cargo sorting and intracellular degradation. By highlighting the underlying molecular processes and concentrating on specific examples, this book reviews the recent emergence of derailed endocytosis and vesicular trafficking as a landmark of cancer. In-depth understanding of this common feature of tumors might lead the way to drug-induced strategies, able to rectify intracellular trafficking in cancer.

More books from Springer New York

Cover of the book Vision and Attention by
Cover of the book Family Medicine by
Cover of the book Integrated Behavioral Health in Primary Care by
Cover of the book Breast Cancer by
Cover of the book The Sun and How to Observe It by
Cover of the book Manual of Upper Gastrointestinal Surgery by
Cover of the book The Polyol Paradigm and Complications of Diabetes by
Cover of the book Topics in Dynamics of Bridges, Volume 3 by
Cover of the book Hyponatremia by
Cover of the book FPGA Design by
Cover of the book Pedophilia by
Cover of the book Practice of Sustainable Community Development by
Cover of the book Children’s Interpersonal Trust by
Cover of the book High Performance Cloud Auditing and Applications by
Cover of the book Statistical Methods for Quality Assurance by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy