Biomarkers in Neoplastic Neuropathology

Nonfiction, Health & Well Being, Medical, Specialties, Pathology, Internal Medicine, Neurology
Cover of the book Biomarkers in Neoplastic Neuropathology by Fausto Rodriguez, Cheng-Ying Ho, Springer International Publishing
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Author: Fausto Rodriguez, Cheng-Ying Ho ISBN: 9783319209319
Publisher: Springer International Publishing Publication: March 4, 2016
Imprint: Springer Language: English
Author: Fausto Rodriguez, Cheng-Ying Ho
ISBN: 9783319209319
Publisher: Springer International Publishing
Publication: March 4, 2016
Imprint: Springer
Language: English

This book is a rich source of information on biomarkers applicable to the pathology of neoplastic disorders of the brain. Thorough descriptions are provided of the techniques currently available for clinical and experimental evaluation of biomarkers in brain neoplasms, including in situ hybridization, array-based methods, methylation profiling, next-generation sequencing, and practical gene panels. Incorporation of multiple biomarkers in the development of molecular subgroups with biologic and therapeutic relevance is also discussed. A section on biobanking covers the equally important topic of optimal preservation of tissue and includes consideration of ethical considerations raised by the use of tissue obtained in clinical settings. The closing section discusses the major categories of neoplastic disorders involving the nervous system, with emphasis on diagnostic, prognostic, and predictive biomarkers used in the pathologic evaluation of different types of brain tumor.

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This book is a rich source of information on biomarkers applicable to the pathology of neoplastic disorders of the brain. Thorough descriptions are provided of the techniques currently available for clinical and experimental evaluation of biomarkers in brain neoplasms, including in situ hybridization, array-based methods, methylation profiling, next-generation sequencing, and practical gene panels. Incorporation of multiple biomarkers in the development of molecular subgroups with biologic and therapeutic relevance is also discussed. A section on biobanking covers the equally important topic of optimal preservation of tissue and includes consideration of ethical considerations raised by the use of tissue obtained in clinical settings. The closing section discusses the major categories of neoplastic disorders involving the nervous system, with emphasis on diagnostic, prognostic, and predictive biomarkers used in the pathologic evaluation of different types of brain tumor.

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