Cellular Therapy of Cancer
Development of Gene Therapy Based Approaches
Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Specialties, Oncology
| Author: | Robert E Hawkins | ISBN: | 9789814618533 |
| Publisher: | World Scientific Publishing Company | Publication: | May 5, 2014 |
| Imprint: | WSPC | Language: | English |
| Author: | Robert E Hawkins |
| ISBN: | 9789814618533 |
| Publisher: | World Scientific Publishing Company |
| Publication: | May 5, 2014 |
| Imprint: | WSPC |
| Language: | English |
Cancer research has progressed enormously in recent years. This review volume will address recent findings in the area of T-cell therapy for cancer, including use of tumour infiltrating lymphocytes (TILs) as a therapy for melanoma, choice of target antigens, advances in engineered receptors, methods of gene transfer to T cells, review of cell processing methods and clinical trial design. Written by leadings scientists in the field, this up-to-date review on cancer research will be an important reference source to the researchers and healthcare professionals in the field.
Contents:
- Challenges of T-Cell Therapy (Naomi Taylor, Anna Mondino and Balbino Alarcon)
- Gene Transfer into T Cells (David Gilham and Hinrich Abken)
- TCR-Engineered T Cells (Reno Debets and Ton Schumacher)
- T-Bodies: Antibody-Based Engineered T-Cell Receptors (John Bridgeman, Andreas A Hombach, David Gilham, Zelig Eshhar and Hinrich Abken)
- T-Cell Engineering and Expansion — GMP Issues (Cor Lamers and Ryan Guest)
- Clinical Trial Design (Robert Hawkins, John Haanen and Fiona Thistlethwaite)
Readership: Cancer researchers, oncologists and healthcare professionals.
Key Features:
- The authors include many of Europe's leading scientists in the field, all of whom contribute to a leading, highly rated, EC funded consortium
- It includes up-to-date results from all aspects of cancer research from basic research to clinical data
- The therapies being developed within this research field have the potential to significantly improve the treatment of many hard to treat cancers and therefore represent a significant step forward in cancer research
Cancer research has progressed enormously in recent years. This review volume will address recent findings in the area of T-cell therapy for cancer, including use of tumour infiltrating lymphocytes (TILs) as a therapy for melanoma, choice of target antigens, advances in engineered receptors, methods of gene transfer to T cells, review of cell processing methods and clinical trial design. Written by leadings scientists in the field, this up-to-date review on cancer research will be an important reference source to the researchers and healthcare professionals in the field.
Contents:
- Challenges of T-Cell Therapy (Naomi Taylor, Anna Mondino and Balbino Alarcon)
- Gene Transfer into T Cells (David Gilham and Hinrich Abken)
- TCR-Engineered T Cells (Reno Debets and Ton Schumacher)
- T-Bodies: Antibody-Based Engineered T-Cell Receptors (John Bridgeman, Andreas A Hombach, David Gilham, Zelig Eshhar and Hinrich Abken)
- T-Cell Engineering and Expansion — GMP Issues (Cor Lamers and Ryan Guest)
- Clinical Trial Design (Robert Hawkins, John Haanen and Fiona Thistlethwaite)
Readership: Cancer researchers, oncologists and healthcare professionals.
Key Features:
- The authors include many of Europe's leading scientists in the field, all of whom contribute to a leading, highly rated, EC funded consortium
- It includes up-to-date results from all aspects of cancer research from basic research to clinical data
- The therapies being developed within this research field have the potential to significantly improve the treatment of many hard to treat cancers and therefore represent a significant step forward in cancer research
