Cholesterol Transporters of the START Domain Protein Family in Health and Disease

START Proteins - Structure and Function

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Endocrinology & Metabolism, Science & Nature, Science, Biological Sciences, Biochemistry
Cover of the book Cholesterol Transporters of the START Domain Protein Family in Health and Disease by , Springer New York
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Author: ISBN: 9781493911127
Publisher: Springer New York Publication: July 24, 2014
Imprint: Springer Language: English
Author:
ISBN: 9781493911127
Publisher: Springer New York
Publication: July 24, 2014
Imprint: Springer
Language: English

Non-vesicular intracellular cholesterol transport is an important mechanism for maintaining membrane cholesterol homeostasis. Recent reports of studies directed at soluble cholesterol transport proteins indicate that aberrant expression of the START proteins may contribute to disease states associated with disorders in cholesterol homeostasis. This is an exciting new direction in the field and the purpose of this book will be to highlight the current research directed at potential roles for the START family in diabetes, cancer and atherogenesis.

This book also provides a personal and historical perspective of the discovery-to-publication journey that the authors had for their particular START domain family member. The goal will be to provide perspectives to graduate students, post-doctoral fellows and endocrinology fellows on the research discovery process.

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Non-vesicular intracellular cholesterol transport is an important mechanism for maintaining membrane cholesterol homeostasis. Recent reports of studies directed at soluble cholesterol transport proteins indicate that aberrant expression of the START proteins may contribute to disease states associated with disorders in cholesterol homeostasis. This is an exciting new direction in the field and the purpose of this book will be to highlight the current research directed at potential roles for the START family in diabetes, cancer and atherogenesis.

This book also provides a personal and historical perspective of the discovery-to-publication journey that the authors had for their particular START domain family member. The goal will be to provide perspectives to graduate students, post-doctoral fellows and endocrinology fellows on the research discovery process.

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